Integrates curated information about mutant mouse lines held as live or cryopreserved stocks from MRC Harwell research and from external data resources. MouseBook can be browsed by catalog or the database can be searched using an intuitive Google-style search engine and searches can be restricted by content-type to genes, variants, imprinting genes or regions and stocks. The users can find items in the database by searching for gene names, key words or ontology terms. The MouseBook web portal also provides the ability to order mutant mouse line stocks.
Collects all available case reports on uniparental disomy (UPD) in clinical cases. UPD is the presence of a chromosome pair derived only from one parent in a disomic cell line. UPD hosts data in tumor cases. Leukemia cases are not reported in this repository. The acquired but non-cancer-related disorders with UPD are also not included. This database provides information for patients and clinicians.
Integrates a comprehensive literature-derived catalog of murine imprinted genes with a genome browser that makes the microarray data immediately accessible in annotation-rich genomic context. WAMIDEX exemplifies the use of the self-organizing map method for the discovery of novel imprinted genes from microarray data. The parent-of-origin-specific expression of imprinted genes is frequently limited to specific tissues or developmental stages, a fact that the atlas reflects in its design and data content.
Focuses on the collection of information concerning mammalian imprinted genes. MetaImprint incorporates 539 imprinted genes, including 255 experimentally confirmed genes, and their detailed research courses from eight mammalian species. MetaImprint also hosts genome-wide genetic and epigenetic information of imprinted genes, including imprinting control regions, single nucleotide polymorphisms (SNPs), non-coding RNAs, DNA methylation and histone modifications. Information related to human diseases and functional annotation was also integrated into MetaImprint. To facilitate data extraction, MetaImprint supports multiple search options, such as by gene ID and disease name. Moreover, a configurable Imprinted Gene Browser was developed to visualize the information on imprinted genes in a genomic context.
Provides a portal into the burgeoning fields of epigenetics and genomic imprinting, collecting relevant articles and reviews, press reports, video and audio lectures, and genetic information. Geneimprint began in 1995 as the M6P/IGF2R Information Core, disseminating information about the first imprinted gene identified to function as a tumor suppressor. Geneimprint is indexed by Thomson Scientific Current Web Contents.
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