ImpulseDE specifications


Unique identifier OMICS_13282
Software type Package/Module
Interface Command line interface
Restrictions to use None
Input data An expression table with genes in rows and samples in columns; An annotation table with two columns, one carrying the timestamps as numeric numbers and the other one carrying the condition information.
Output data Fitted impulse model parameters, sum of squared fitting errors as well as the calculated impulse values for all time points; genes differentially expressed according to a specified cutoff together with the adjusted p-values; the adjusted p-values, flags and results of additional tests for all genes; clusters, to which the genes were assigned to, the mean expression values for the clusters.
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.0.0
Stability Stable
Requirements graphics, grDevices, stats, utils, parallel, compiler
Maintained Yes



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  • person_outline Nir Yosef <>

ImpulseDE article

ImpulseDE institution(s)
Genomics and Immunoregulation, LIMES-Institute, University of Bonn, Bonn, Germany; Electrical Engineering and Computer Science, Center for Computational Biology, University of California Berkeley, CA, USA
ImpulseDE funding source(s)
This work was supported by grants U01 MH105979 and U01 HG007910 from the National Institute of Health and partially by SFB704.

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