InferPPI statistics

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Associated diseases

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InferPPI specifications

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Unique identifier OMICS_24035
Name InferPPI
Alternative name Inferring Protein-Protein Interactions
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes

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  • person_outline Luonan Chen <>

InferPPI in publications

 (4)
PMCID: 5642621
PMID: 29050346
DOI: 10.18632/oncotarget.20537

[…] to cope with a mount of biological problems, for instance, to clarify complicated biological network [–] and to identifycandidate genes [, ]. for example, huang et al. presented a model for inferring protein-protein interactions based on protein-protein correlation utilizing least squares regression []. zhu et al. proposed a robust geometric approach for modeling protein-protein […]

PMCID: 3532072
PMID: 23244412
DOI: 10.1186/1756-0500-5-472

[…] of building msas by finding homologous sequences of two proteins known to be in complex, and then pairing the sequences originating from the same species, is not feasible for the following reasons. inferring protein-protein interactions across species based on sequence homology has a low level of accuracy, requiring a sequence identity of far higher than 70% []. using only sequences […]

PMCID: 3221619
PMID: 22024468
DOI: 10.1186/2043-9113-1-28

[…] network inference tool (grninfer), gene regulatory network reconstruction tool with compound targets (ngntinfer), inferring transcriptional regulatory networks from high-throughput data (ntrninfer), inferring protein-protein interactions by parsimony principle (ninferppi), inferring protein-protein interactions based on multi-domain cooperation (nmdcinfer), molecular network aligner […]

PMCID: 1360688
PMID: 16420696
DOI: 10.1186/1471-2105-7-24

[…] network space. it is well known that the correlation of two protein distance spaces is a marker of some form of interaction between the two molecules [], and this feature is routinely adopted for inferring protein-protein interactions []. the need to support a viable interaction between two proteins imposes a mutual constraint (resulting into a covariation) to the random mutation drift […]


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