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For a given protein sequence or structure query, it reports protein-protein, protein-small molecule, protein nucleic acids and protein-ion interactions observed in experimentally-determined structural biological assemblies. IBIS also infers/predicts interacting partners and binding sites by homology, by inspecting the protein complexes formed by close homologs of a given query. To ensure biological relevance of inferred binding sites, the IBIS algorithm clusters binding sites formed by homologs based on binding site sequence and structure conservation.

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IBIS classification

IBIS specifications

Unique identifier:
OMICS_01917
Interface:
Web user interface
Input data:
Enter a protein PDB ID, Accession, or GI
Stability:
Stable
Name:
Inferred Biomolecular Interactions Server
Restrictions to use:
None
Computer skills:
Basic
Maintained:
Yes

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Publications

Institution(s)

National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA

Funding source(s)

National Institutes of Health/Department of Health and Human Service (DHHS) (Intramural Research program of the National Library of Medicine)

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