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ODE model / Ordinary Differential Equations model
Provides a model for antibody dependent cellular cytotoxicity (ADCC). ODE model can extract natural killer (NK) cells kill tumour cells from in vitro cytotoxicity data by applying perturbation methods. It is able to relate the rate at which NK cells kill in response to binding antibody with the percentage of cancer cells killed at the end of a cytotoxicity assay. This tool can predict how different initial antibody levels yield different information about the functional form of the kill rate function.
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