Allows investigation of the mammalian innate immune response. InnateDB provides innate immunity interactions, pathways and their component molecules that are manually curated. It contains more than 18 000 InnateDB-curated molecular interactions from the review of over 3000 published articles. This database integrates pathways of relevance to allergy and asthma. It can be used to discover relationships between innate immunity and other processes.
Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada; Animal & Bioscience Research Department, AGRIC, Teagasc, Grange, Dunsany, County Meath, Ireland; Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
InnateDB funding source(s)
Supported by Genome BC through the Pathogenomics of Innate Immunity (PI2) project and by the Foundation for the National Institutes of Health and the Canadian Institutes of Health Research under the Grand Challenges in Global Health Research Initiative [Grand Challenges ID: 419]; by AllerGen grants 12ASI1 and 12B&B2; by a postdoctoral trainee award from the Michael Smith Foundation for Health Research (MSFHR) and by a MSFHR Senior Scholar and a Canada Research Chair (CRC).