INSIGHT statistics

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Associated diseases

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INSIGHT specifications

Information


Unique identifier OMICS_20256
Name INSIGHT
Alternative names Inference of Natural Selection from Interspersed Genomically coHerent elemenTs, FitCons (Fitness Consequences)
Interface Web user interface
Restrictions to use None
Input format BED
Programming languages C
Computer skills Basic
Stability Stable
Maintained Yes

Documentation


Maintainers


  • person_outline Adam Siepel <>
  • person_outline Ilan Gronau <>
  • person_outline Ilan Gronau <>

Additional information


http://compgen.cshl.edu/INSIGHT/overview.php

Information


Unique identifier OMICS_20256
Name INSIGHT
Alternative names Inference of Natural Selection from Interspersed Genomically coHerent elemenTs, FitCons (Fitness Consequences)
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C
Computer skills Advanced
Version 1.1
Stability Stable
Source code URL http://compgen.cshl.edu/INSIGHT/downloads/INSIGHT-v1_1.tar.gz
Maintained Yes

Versioning


Add your version

Documentation


Maintainers


  • person_outline Adam Siepel <>
  • person_outline Ilan Gronau <>
  • person_outline Ilan Gronau <>

Additional information


http://compgen.cshl.edu/INSIGHT/overview.php

Publication for Inference of Natural Selection from Interspersed Genomically coHerent elemenTs

INSIGHT in publication

PMCID: 5485531
PMID: 28635624
DOI: 10.3390/genes8060167

[…] [], tools such as combined annotation–dependent depletion (cadd) [], deleterious annotation of genetic variants (dann) [], functional analysis through hidden markov models (fathmm) [], and linear inference of natural selection from interspersed genomically coherent elements (linsight) [] have been developed to predict functionality of variants outside the coding regions. these tools are based […]


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INSIGHT institution(s)
Graduate Field of Computer Science, Cornell University, Ithaca, NY, USA; Department of Biological Statistics & Computational Biology, Cornell University, Ithaca, NY, USA
INSIGHT funding source(s)
Supported by NIH grant GM102192, a David and Lucile Packard Fellowship for Science and Engineering, and a postdoctoral fellowship from the Cornell Center for Comparative and Population Genomics.

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