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IntEnz specifications


Unique identifier OMICS_02684
Name IntEnz
Alternative name Integrated relational Enzyme database
Restrictions to use None
Maintained Yes


  • person_outline Astrid Fleischmann

Publication for Integrated relational Enzyme database

IntEnz citations


PDBe: towards reusable data delivery infrastructure at protein data bank in Europe

Nucleic Acids Res
PMCID: 5753225
PMID: 29126160
DOI: 10.1093/nar/gkx1070

[…] FTS (Structure Integration with Function, Taxonomy and Sequence, ()), a resource providing residue-level mapping between UniProt KnowledgeBase (UniProtKB) and PDB entries, as well as annotations from IntEnz (), GO (), Pfam (), InterPro (), SCOP (), CATH () and the NCBI taxonomy resources (). Recently, PDBe has carried out a number of improvements to the way SIFTS mappings are derived and presented […]


Reactome pathway analysis: a high performance in memory approach

BMC Bioinformatics
PMCID: 5333408
PMID: 28249561
DOI: 10.1186/s12859-017-1559-2

[…] ities, filled in during curation, Reactome queries Orphanet, Protein Ontology (PRO), IntAct, RHEA, DOCKBlaster, FlyBase, The Human Metabolome Database (HMDB), Zinc, KEGG, UniProt, ENSEMBL, BRENDA and IntEnz to get their cross-references for entities annotated in Reactome. Both, curated and cross-referenced identifiers are included in the analysis lookup table, as explained in the Implementation se […]


Comparative Genomic and Transcriptomic Analysis of Wangiella dermatitidis, A Major Cause of Phaeohyphomycosis and a Model Black Yeast Human Pathogen

PMCID: 4059230
PMID: 24496724
DOI: 10.1534/g3.113.009241

[…] mine 6-dehydrogenases (UNGD) UDP-glucose 6-dehydrogenases (UGD), and several experimentally characterized bacterial nucleotide sugar dehydrogenases. Previously classified bacterial sequences from the Integrated relational Enzyme database ( () were compared to fungal genes; these include one UDP-N-acetylglucosamine 6-dehydrogenase (UNGD; EC: from Pseudomonas aerugi […]


Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio computational analysis

PMCID: 3258480
PMID: 21605342
DOI: 10.1111/j.1742-4658.2011.08190.x

[…] Each complete EC number (node) was determined from the IntEnz database []. We only included enzymes with a complete, four-digit EC numbers that have been manually curated (i.e. Swiss-Prot entries) [] using the UniProtKB flat-files (the data were last down […]


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IntEnz institution(s)
EMBL Outstation--European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

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