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Publication for InterDom
Toward a systems level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria
[…] hocystis 6803). It includes 109,532 predicted protein-protein interactions extracted from the databases STRING (2658 proteins, 26,805 interactions), PSIMAP-based (1028 proteins, 12,748 interactions), InterDom (1760 proteins, 80,319 interactions) and iPfAM (1541 proteins, 13,448 interactions) (Kim et al., ). The SynechoNET visualization interface also permits the exploration of a “high confidence” […]
DomainRBF: a Bayesian regression approach to the prioritization of candidate domains for complex diseases
[…] terms of precision, mean rank ratio, and AUC scores. We perform this ab initio inference using the large network that is composed of entire interactions in DOMINE and high-confidence interactions in InterDom (with diffusion kernel), and we summarize the results in Table .In comparison with the results in Table , we find that the performance of the domainRBF approach slightly drops (less than 4%). […]
Gene prioritization in Type 2 Diabetes using domain interactions and network analysis
[…] ure of the interaction network.Therefore, HWEs were further ranked by using Ci < 0.015 hypothesizing that those candidates below this Ci could be probable disease candidates classifying them as HWEc. InterDom domain interactions (with a confidence score of interactions ≥10) were used for calculating the Ci in NetworkAnalyzer . […]
ProKware: integrated software for presenting protein structural properties in protein tertiary structures
[…] The protein sequences, domain/motifs, protein–protein interacting domains, protein tertiary structures and post-translational modifications were obtained from Swiss-Prot (), InterPro (), InterDom (), PDB (), DIP (), MINT () and dbPTM (), respectively ().The Protein Data Bank (PDB) () is a worldwide database that deposits the 3D coordinates of protein structures. Numerous databases, su […]
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