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InterDom specifications


Unique identifier OMICS_02915
Name InterDom
Restrictions to use Academic or non-commercial use
Maintained No

Publication for InterDom

InterDom citations


Toward a systems level understanding of gene regulatory, protein interaction, and metabolic networks in cyanobacteria

Front Genet
PMCID: 4079066
PMID: 25071821
DOI: 10.3389/fgene.2014.00191

[…] hocystis 6803). It includes 109,532 predicted protein-protein interactions extracted from the databases STRING (2658 proteins, 26,805 interactions), PSIMAP-based (1028 proteins, 12,748 interactions), InterDom (1760 proteins, 80,319 interactions) and iPfAM (1541 proteins, 13,448 interactions) (Kim et al., ). The SynechoNET visualization interface also permits the exploration of a “high confidence” […]


DomainRBF: a Bayesian regression approach to the prioritization of candidate domains for complex diseases

BMC Syst Biol
PMCID: 3108930
PMID: 21504591
DOI: 10.1186/1752-0509-5-55

[…] terms of precision, mean rank ratio, and AUC scores. We perform this ab initio inference using the large network that is composed of entire interactions in DOMINE and high-confidence interactions in InterDom (with diffusion kernel), and we summarize the results in Table .In comparison with the results in Table , we find that the performance of the domainRBF approach slightly drops (less than 4%). […]


Gene prioritization in Type 2 Diabetes using domain interactions and network analysis

BMC Genomics
PMCID: 2824729
PMID: 20122255
DOI: 10.1186/1471-2164-11-84

[…] ure of the interaction network.Therefore, HWEs were further ranked by using Ci < 0.015 hypothesizing that those candidates below this Ci could be probable disease candidates classifying them as HWEc. InterDom domain interactions (with a confidence score of interactions ≥10) were used for calculating the Ci in NetworkAnalyzer []. […]


ProKware: integrated software for presenting protein structural properties in protein tertiary structures

Nucleic Acids Res
PMCID: 1538827
PMID: 16845116
DOI: 10.1093/nar/gkl235

[…] The protein sequences, domain/motifs, protein–protein interacting domains, protein tertiary structures and post-translational modifications were obtained from Swiss-Prot (), InterPro (), InterDom (), PDB (), DIP (), MINT () and dbPTM (), respectively ().The Protein Data Bank (PDB) () is a worldwide database that deposits the 3D coordinates of protein structures. Numerous databases, su […]


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InterDom institution(s)
Biocomputing Group, Laboratories for Information Technology, Singapore Genome Institute of Singapore, Singapore

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