Contains records of known RNA 3D motifs as well as records for clusters of bases that are interconnected by hydrogen bonds. The contents of the database were compiled from RNA structural annotations carried out by the NASSAM and COGNAC computer programs. Users have the choice of three searching methods: (i) an option to select a pre-determined set of arrangements and motifs; (ii) an option to search for base interaction annotations in a specific PDB structure using a PDB ID query or by using the unique database identifier; and (iii) a keyword search option. An analysis of the database content and comparisons with the existing corpus of knowledge regarding RNA 3D motifs clearly show that InterRNA is able to provide an extension of the annotations for known motifs as well as able to provide novel interactions for further investigations.
School of Biosciences and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM Bangi, Selangor, Malaysia; Department of Artificial Intelligence, Faculty of Computer Science and Information Technology, University of Malaya, Kuala Lumpur, Malaysia; Institute of Systems Biology, Universiti Kebangsaan Malaysia, UKM Bangi, Selangor, Malaysia
InterRNA funding source(s)
Universiti Kebangsaan Malaysia [ICONIC-2013-007]; University Malaya High Impact Research MOE Grant [UM.C/625/1HIR/MoE/FCSIT/002—Acc. No.: B222001]; Ministry of Science, Technology and Innovation [02-01-02-SF1278]