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IPA specifications

Information


Unique identifier OMICS_00399
Name IPA
Alternative name Ingenuity Pathway Analysis
Software type Toolkit/Suite
Interface Command line interface, Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux, Mac OS, Windows
License Commercial
Computer skills Advanced
Stability Stable
Maintained Yes

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IPA citations

 (2507)
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Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross linking

2018
Nat Commun
PMCID: 5959879
PMID: 29777108
DOI: 10.1038/s41467-018-04355-w
call_split See protocol

[…] Using ingenuity pathway analysis (IPA) (http://www.ingenuity.com/products/ipa) of the genes (n = 403) that are generally hyper-expressed (see the definition of hyper-expression given in section “Analysis of […]

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“Tuberculosis in advanced HIV infection is associated with increased expression of IFNγ and its downstream targets”

2018
BMC Infect Dis
PMCID: 5952419
PMID: 29764370
DOI: 10.1186/s12879-018-3127-4
call_split See protocol

[…] cal clustering was performed with the gplots package in R. The ROC curve was plotted with the pROC package in R. Functional and network analyses of differentially expressed genes were performed using Ingenuity Pathway Analysis (IPA, Ingenuity Systems, https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/, Redwood City, CA). […]

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Altered lung biology of healthy never smokers following acute inhalation of E cigarettes

2018
PMCID: 5950177
PMID: 29754582
DOI: 10.1186/s12931-018-0778-z
call_split See protocol

[…] NA-seq data was also used to identify expression of nAChR in the SAE and AM. The molecular pathways associated with the significant genes impacted by acute aerosol inhalation of EC was examined using Ingenuity Pathway Analysis. […]

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Cross ancestry genome wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases

2018
Nat Commun
PMCID: 5951816
PMID: 29760442
DOI: 10.1038/s41467-018-03646-6

[…] nally revealed the endoplasmic-reticulum-associated protein degradation (ERAD) pathway (GO:0036503) (Supplementary Data ). The ERAD pathway also emerged as an overrepresented canonical pathway in the Ingenuity Pathway Analysis (IPA) (Supplementary Fig. ), along with pathways related to connective tissue disorders and metabolism (Supplementary Tables , ).The FUMA platform (https://ctg.cncr.nl/softw […]

library_books

Recently evolved human specific methylated regions are enriched in schizophrenia signals

2018
BMC Evol Biol
PMCID: 5946405
PMID: 29747567
DOI: 10.1186/s12862-018-1177-2

[…] Pathway analysis was performed using Ingenuity Pathway Analysis (IPA) from QIAGEN (https://www.qiagen.com/no/shop/analytics-software/biological-data-tools/ingenuity-pathway-analysis/, last accessed 26th August 2016). The reference set wa […]

library_books

SolCyc: a database hub at the Sol Genomics Network (SGN) for the manual curation of metabolic networks in Solanum and Nicotiana specific databases

2018
PMCID: 5946812
PMID: 29762652
DOI: 10.1093/database/bay035

[…] nisms (, ).Concomitant with the increasing ease of access to new genomes and the need for functional interpretation of Omics data, the number of metabolic databases has also expanded. Reactome () and Ingenuity Pathway analysis (www.ingenuity.com), e.g. integrate mostly animal and human pathways, while the Kyoto Encyclopedia of Genes and Genomes (KEGG) () aims to be a universal metabolic database i […]

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