iPathwayGuide statistics

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Citations per year

Number of citations per year for the bioinformatics software tool iPathwayGuide

Tool usage distribution map

This map represents all the scientific publications referring to iPathwayGuide per scientific context
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Associated diseases

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Popular tool citations

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iPathwayGuide specifications


Unique identifier OMICS_05011
Name iPathwayGuide
Alternative name PathwayGuide
Software type Application/Script
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Unix/Linux
License Commercial
Computer skills Medium
Stability Stable
Registration required Yes
Maintained Yes


  • Primates
    • Homo sapiens


No version available



  • person_outline PathwayGuide Team

Additional information

https://advaitabio.com/ipathwayguide-faqs/ https://advaitabio.com/ipathwayguide-tutorials/

iPathwayGuide citations


A Novel S100A8/A9 Induced Fingerprint of Mesenchymal Stem Cells associated with Enhanced Wound Healing

Sci Rep
PMCID: 5906602
PMID: 29670130
DOI: 10.1038/s41598-018-24425-9

[…] e down-regulated in S100A8/A9 treated MSCs during 6 and 24 h. To further study the pathways which are different in S100A8/A9 treated MSCs compared to control MSCs, Impact analysis was performed using iPathwayGuide and the Gene trail tool (Fig. ). Seven major pathways were uncovered in S100A8/A9 treated MSCs using topological analysis. The most significant pathways included cell motility, cell/leuk […]


Bronchoalveolar lavage (BAL) cells in idiopathic pulmonary fibrosis express a complex pro inflammatory, pro repair, angiogenic activation pattern, likely associated with macrophage iron accumulation

PLoS One
PMCID: 5896901
PMID: 29649237
DOI: 10.1371/journal.pone.0194803

[…] 88 differentially expressed genes (Table A in ).Gene Ontology and Pathway analysis of differentially expressed genes in IPF, was performed using the iPathways web resource (http://www.advaitabio.com/ipathwayguide) with the Gene Ontology (GO) Consortium database (Release 09/19/2014) and the (Kyoto Encyclopedia of Genes and Genomes, KEGG, database, Release 78.0+/06-02, Jun 16) [], using the 88 gene […]


The Plasticizer Bisphenol A Perturbs the Hepatic Epigenome: A Systems Level Analysis of the miRNome

PMCID: 5664119
PMID: 29027980
DOI: 10.3390/genes8100269

[…] × 10−3), and Inner mitochondrial membrane protein complex (q = 1.85 × 10−3) (). From the 1491 DE zebrafish genes, 1211 have human orthologs that we used as input for system level analysis in Advaita-iPathwayGuide (). In summary, 2 pathways and 2 cellular component GO terms were found to be significantly enriched (). Adherens junction (q = 0.07, ) and Oxidative phosphorylation (q = 0.07, ) were in […]


Enhanced Therapeutic Treatment of Colorectal Cancer Using Surface Modified Nanoporous Acupuncture Needles

Sci Rep
PMCID: 5635022
PMID: 29018212
DOI: 10.1038/s41598-017-11213-0

[…] Supplementary Table  shows, compared to I1, the differentially expressed genes (DEGs) in I2–I6. Pathways that were significantly changed (p < 0.05) in each group compared to I1, determined using the iPathwayGuide program, are listed in Supplementary Table . Based on statistically significant fold changes, the number of DEGs selected in I2 was 46. In I3 and I4, 21 and 69 genes were, respectively, […]


Nutrient supply affects the mRNA expression profile of the porcine skeletal muscle

BMC Genomics
PMCID: 5553784
PMID: 28797239
DOI: 10.1186/s12864-017-3986-x
call_split See protocol

[…] tion for multiple testing is achieved by using a false discovery rate approach []. We considered as differentially expressed (DE) those mRNAs displaying a |FC| > 1.5 and a q-value <0.05.Advaita Bio’s iPathwayGuide (http://www.advaitabio.com/ipathwayguide) and the Cytoscape software [] combined with the ReactomeFIViz app [] were used to infer if certain gene ontology terms and pathways are enriched […]


SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes

Sci Rep
PMCID: 5481408
PMID: 28642596
DOI: 10.1038/s41598-017-04369-2
call_split See protocol

[…] as performed using the heatmap.3 function from the GMD R package. The raw htseq-counts were first normalized using variance stabilizing transformation from the DESeq2 package before cluster analysis. iPathwayGuide (Advaita bioinformatics) and DAVID Bioinformatics, web-based analysis tools were further employed to identify the top biological pathways and metabolic pathways respectively. KEGG pathwa […]

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iPathwayGuide institution(s)
Advaita Corporation, Plymouth, MI, USA

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