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IPD-MHC specifications


Unique identifier OMICS_14128
Alternative name Immuno Polymorphism Database-Major Histocompatibility Complex
Restrictions to use None
Database management system MySQL
Content license CC Attribution-NonCommercial-NoDerivs
Maintained Yes


  • person_outline Steven Marsh

Publication for Immuno Polymorphism Database-Major Histocompatibility Complex

IPD-MHC citations


A novel B and helper T cell epitopes based prophylactic vaccine against Echinococcus granulosus

PMCID: 5915707
PMID: 29713601
DOI: 10.15171/bi.2018.06

[…] Amino acid sequences of DLA-DRB1*01501 and DRB1*01101 were retrieved from IPD-MHC database (https://www.ebi.ac.uk/ipd/mhc/). The tertiary structures of MHC alleles were modeled using I-TASSER online server. The DLA-DRB1*01501 model was energy minimized via Swiss-PdbViewer s […]


Discovery of gorilla MHC C expressing C1 ligand for KIR

PMCID: 5899755
PMID: 29101448
DOI: 10.1007/s00251-017-1038-y

[…] Full-length coding region sequences of the chimpanzee (Patr-B and -C), bonobo (Papa-B and -C), gorilla (Gogo-B, -C and Gobe-B, -C), and orangutan (Popy-B, -C, and Poab-B, -C) were retrieved from the IPD-MHC database (Maccari et al. ). Using the program MAFFT (Katoh et al. ), we generated an alignment which was used to reconstruct a neighbor-joining tree based on the Tamura-Nei model with 500 boot […]


Prediction and in vitro verification of potential CTL epitopes conserved among PRRSV 2 strains

PMCID: 5597684
PMID: 28589207
DOI: 10.1007/s00251-017-1004-8

[…] rrently, 216 SLA class I alleles are known, including 62 SLA-1, 61 SLA-2, and 32 SLA-3 alleles. The majority of the SLA alleles are published in the Immune Polymorphism Database (http://www.ebi.ac.uk/ipd/mhc/sla/). This number is relatively small compared to the known human MHC-I diversity counting several thousand proteins and is likely to be a consequence of scientific focus and limited genetic […]


Swine Leukocyte Antigen Diversity in Canadian Specific Pathogen Free Yorkshire and Landrace Pigs

Front Immunol
PMCID: 5350106
PMID: 28360911
DOI: 10.3389/fimmu.2017.00282

[…] polymorphic class II alleles (91 DRB1 and 54 DQB1) have been designated by the SLA Nomenclature Committee of the International Society for Animal Genetics (ISAG) in the Immuno Polymorphism Database (IPD)-MHC SLA sequence database.Yorkshire and Landrace pigs are widely distributed in the world. When every country develops breeding according to their need, characteristics of natural populations are […]


Identification of Theileria lestoquardi Antigens Recognized by CD8+ T Cells

PLoS One
PMCID: 5017765
PMID: 27611868
DOI: 10.1371/journal.pone.0162571

[…] class II genotyping was carried out as previously described []. The novel class II DRB1 sequence was validated by cloning the complete second exon sequence. The sequence was submitted to the ENA and IPD-MHC database for an official allelic nomenclature. […]


First evidence of hybridization between golden jackal (Canis aureus) and domestic dog (Canis familiaris) as revealed by genetic markers

R Soc Open Sci
PMCID: 4807452
PMID: 27019731
DOI: 10.1098/rsos.150450

[…] Biosystems SeqScape® software, which is designed for analysis based on a locus-specific allele reference library, and previously described canid alleles that we obtained from the Immuno Polymorphism (IPD)—MHC Database (L. J. Kennedy 2013, personal communication), as described in Arbanasić et al. []. Three-locus haplotypes were unambiguously identified in a sequential process [] and confirmed by Ar […]


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IPD-MHC institution(s)
The Pirbright Institute, Surrey, UK; Anthony Nolan Research Institute, Royal Free Hospital, London, UK; UCL Cancer Institute, Royal Free Campus, London, UK; Moredun Research Institute, Pentlands Science Park, Midlothian, UK; Stanford University, Stanford, CA, USA; Norwegian Veterinary Institute, Oslo, Norway; University of Cambridge, Cambridge, UK; Gift of Life Michigan, Ann Arbor, MI, USA; Biomedical Primate Research Centre, Rijswijk, Netherlands; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK
IPD-MHC funding source(s)
Biotechnology and Biological Sciences Research Council (BBSRC) [BB/M011488/1]; European Molecular Biology Laboratories, International Society for Animal Genetics (ISAG) and the Veterinary Immunology Committee (VIC); Scottish Government

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