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Protocols

iProClass specifications

Information


Unique identifier OMICS_02710
Name iProClass
Restrictions to use None
Database management system Oracle
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes

Documentation


Maintainer


  • person_outline iProClass Team

Publication for iProClass

iProClass citations

 (16)
library_books

Quantitative Proteomics of Spodoptera frugiperda Cells during Growth and Baculovirus Infection

2011
PLoS One
PMCID: 3196586
PMID: 22039490
DOI: 10.1371/journal.pone.0026444

[…] to the gene ontology (GO) vocabulary. Since not all 648 entries could be assigned a PIRSF designation, the more general subset of proteins that could retrieve GO annotations using the online resource iProClass was used. For an unbiased compilation, the 15 most abundant terms in each class are shown without further curation. It is shown that 576 proteins were assigned to at least one molecular fun […]

library_books

Calcium/calmodulin kinase1 and its relation to thermotolerance and HSP90 in Sporothrix schenckii: an RNAi and yeast two hybrid study

2011
BMC Microbiol
PMCID: 3146815
PMID: 21745372
DOI: 10.1186/1471-2180-11-162

[…] PANTHERdb.org  []. On-line database searches and comparisons for SSDCL-1 and SSHSP90 were performed with Integrated Protein Classification (iProClass) database http://pir.georgetown.edu/pirwww/dbinfo/iproclass.shtml  [] and the BLAST algorithm http://www.ncbi.nlm.nih.gov/BLAST/ with a cutoff of 10-7, a low complexity filter and the BLOSUM 62 matrix []. Multiple sequence alignments were built using […]

library_books

Representative Proteomes: A Stable, Scalable and Unbiased Proteome Set for Sequence Analysis and Functional Annotation

2011
PLoS One
PMCID: 3083393
PMID: 21556138
DOI: 10.1371/journal.pone.0018910

[…] iProClass is an integrated data-warehouse containing all UniProtKB proteins and additional proteins from NCBI resources . The proteins from the defined representative proteome sets are indexed in iPro […]

call_split

Interaction of the heterotrimeric G protein alpha subunit SSG 1 of Sporothrix schenckii with proteins related to stress response and fungal pathogenicity using a yeast two hybrid assay

2010
BMC Microbiol
PMCID: 3018405
PMID: 21143936
DOI: 10.1186/1471-2180-10-317
call_split See protocol

[…] []. On-line database searches and comparisons for SsSOD, SsGAPDH, SsSit and SsNramp were performed with Integrated Protein Classification (iProClass) database (http://pir.georgetown.edu/pirwww/dbinfo/iproclass.shtml) [] and the BLAST algorithm (http://www.ncbi.nlm.nih.gov/BLAST/) with a cutoff of 10-7, a low complexity filter and the BLOSUM 62 matrix []. Transmembrane helices were identified using […]

library_books

Protein Bioinformatics Infrastructure for the Integration and Analysis of Multiple High Throughput “omics” Data

2010
Adv Bioinformatics
PMCID: 2847380
PMID: 20369061
DOI: 10.1155/2010/423589

[…] iProClass integrated database provides two types of summary report for the information presentation: Protein summary report and Family summary report. The Protein summary report contains information a […]

library_books

Systems Integration of Biodefense Omics Data for Analysis of Pathogen Host Interactions and Identification of Potential Targets

2009
PLoS One
PMCID: 2745575
PMID: 19779614
DOI: 10.1371/journal.pone.0007162

[…] larity at the DNA level (either pseudogenes or unannotated genes) using tBLASTn against the NCBI nr database. Using NCBI's nr which is produced independently of similar, but not identical, sources as iProClass also helps assure no sequences were missing from our warehouse. This additional analysis resulted in a total of 10 Bacillus anthracis specific proteins proposed as high-quality targets for d […]

Citations

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iProClass institution(s)
Georgetown University Medical Center, Preclinical Building, Washington, WA, USA; National Biomedical Research Foundation, Washington, WA, USA
iProClass funding source(s)
Supported by grant DBI-0138188 from National Science Foundation and grant U01-HG02712 from National Institutes of Health.

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