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|Alternative name||Immune Response In Silico|
|Restrictions to use||None|
|User data submission||Not allowed|
- Homo sapiens
Publication for Immune Response In Silico
Similar Source of Differential Blood mRNAs in Lung Cancer and Pulmonary Inflammatory Diseases: Calls for Improved Strategy for Identifying Cancer Specific Biomarkers
[…] To determine whether the myeloid and lymphoid cell proportions differ in the PWB of pulmonary disease patients, we quantified the proportions of myeloid cells and lymphoid cells documented in the Immune Response in Silico (IRIS) database by a process of deconvolution . If B represents the known matrix of microarray expression profiles measured for a disease, comprising both disease and health […]
Deconvolution of the Gene Expression Profiles of Valuable Banked Blood Specimens for Studying the Prognostic Values of Altered Peripheral Immune Cell Proportions in Cancer Patients
[…] ts and the marker genes specifically expressed on B lymphocytes, T lymphocytes, natural killer (NK) lymphocytes, dendritic cells (DCs) and monocytes (excluding monocyte-derived DCs) documented in the Immune Response in Silico (IRIS) database , we evaluated the proportions of the five immune cells, which together make up 100% of PBMC, using a modified semi-supervised nonnegative matrix factorizatio […]
Deconvolution of Blood Microarray Data Identifies Cellular Activation Patterns in Systemic Lupus Erythematosus
[…] be purified in order to construct expression signatures to use as bases for analysis. We have previously reported the purification and microarray analysis of a large collection of white blood cells (Immune Response In Silico, or “IRIS”) . These data include expression of genes in different activation and differentiation states that represent a spectrum of cell species present in blood, providing […]
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