Allows evaluation of Multiple Sequence Alignment (MSA) using structural information. iRMSD-APDB, provided a data set containing at least two structures, returns an evaluation of the considered alignment that takes into account the quality of the implied structural superposition. The software is suitable for evaluating and comparing sequence alignment methods without a need for pre-established reference alignment collections. It is part of the T-Coffee web-server.
Centre For Genomic Regulation (Pompeu Fabra University), Barcelona, Spain; Vital-IT, Swiss Institute of Bioinformatics, Lausanne, Switzerland; Department of Ecology and Evolution, Biophore, Lausanne University, Lausanne, Switzerland; Department of Computer Science and Industrial Engineering, University of Lleida, Lleida, Spain