Predicts whether a SNP is an rSNP. For a given SNP, and using a statistical framework, is-rSNP can successfully predict the set of TFs for which binding is affected. It provides the statistical power to scan large numbers of SNPs, making it suitable to use to screen all associated SNPs output by a typical GWAS.
Department of Computer Science and Software Engineering; NICTA, Victoria Research Lab, The University of Melbourne, Victoria; Bioinformatics and Systems Integration, The Blood and DNA Profiling Facility, Baker IDI Heart and Diabetes Institute, Prahran, Victoria; Metastasis Research Lab, Peter MacCallum Cancer Centre, St Andrews Place, East Melbourne, Victoria; Department of Biochemistry and Molecular Biology. The University of Melbourne, Victoria, Australia