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Isoelectric point detection software tools | Protein physicochemical properties data analysis

For a macromolecular polyprotic system—such as protein, DNA or RNA—the isoelectric or isoionic point—commonly referred to as the isoelectric point (pI)—can be defined by the point of singularity in a titration curve, corresponding to the solution pH value at which the net overall surface charge, and thus, the mobility, of the ampholyte sums to zero (Maldonado et al., 2010). Source text: Bunkute et al., 2015

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