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Protein isoelectric point prediction software tools | Sequence analysis

For a macromolecular polyprotic system—such as protein, DNA or RNA—the isoelectric or isoionic point—commonly referred to as the isoelectric point (pI)—can be defined by the point of singularity in a titration curve,…
Proteome-pl
Dataset

Proteome-pl

An online database containing information about predicted isoelectric points…

An online database containing information about predicted isoelectric points calculated using 18 methods. Proteome-pI allows the retrieval of virtual 2D-PAGE plots and the development of customised…

pICalculax
Desktop

pICalculax

Handles chemical modification effectively by combining bio- and…

Handles chemical modification effectively by combining bio- and chemo-informatics handling of the molecules. pICalculaX can include modifications of peptides in isoelectric point (pI) calculations.…

pIR
Desktop

pIR

An R package to analyze the isoelectric point of peptides and proteins based on…

An R package to analyze the isoelectric point of peptides and proteins based on experimental values and predicted using different functions. pIR provides a statistical framework to analyze the…

ProMoST
Web

ProMoST

Calculates the effect of single or multiple post-translational modifications…

Calculates the effect of single or multiple post-translational modifications (PTMs) on protein isoelectric point (pI) and molecular weight and displays the calculated patterns as two-dimensional (2D)…

IPC
Web
Desktop

IPC Isoelectric Point Calculator

A web service for the estimation of pI using different sets of dissociation…

A web service for the estimation of pI using different sets of dissociation constant (pKa) values, including two new, computationally optimized pKa sets. According to the presented benchmarks, IPC…

PIP-DB
Dataset

PIP-DB Protein Isoelectric Point Database

Catalogues comprehensively the isoelectric points (pIs) of proteins. Protein pI…

Catalogues comprehensively the isoelectric points (pIs) of proteins. Protein pI data were collected through scrutiny of the primary scientific literature. PIP-DB contains 5773 protein entries, each…

pIPredict
Desktop

pIPredict

A computer tool for predicting isoelectric points of peptides and proteins.…

A computer tool for predicting isoelectric points of peptides and proteins. pIPredict is mainly based on the use of the Henderson-Hasselbalch equation and includes a module of prediction using…

Iep
Desktop

Iep

Calculates the isoelectric point of proteins. iep can plot the ionization curve…

Calculates the isoelectric point of proteins. iep can plot the ionization curve with respect to pH and write an output file of the data, where for each pH point the number of bound electrons and…

ProtParam
Web

ProtParam

Allows the computation of various physical and chemical parameters for a given…

Allows the computation of various physical and chemical parameters for a given protein stored in Swiss-Prot or TrEMBL or for a user entered protein sequence. The computed parameters include the…

pI calculator
Desktop

pI calculator

Permits to calculate pKs values of phosphopeptides separated under different…

Permits to calculate pKs values of phosphopeptides separated under different experimental conditions. pI calculator was created on the basis of an experimental dataset containing the most common…

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