Unlock your biological data


Try: RNA sequencing CRISPR Genomic databases DESeq

1 - 2 of 2 results
filter_list Filters
language Programming Language
healing Disease
settings_input_component Operating System
tv Interface
computer Computer Skill
1 - 2 of 2 results
A method to infer isoform-specific co-expression networks from exon-level RNA-Seq data, using large dimensional trace. SpliceNet goes beyond differentially expressed genes and infers splicing isoform network changes between normal and diseased samples. It eases the sample size bottleneck; evaluations on simulated data and lung cancer-specific ERBB2 and MAPK signaling pathways, with varying number of samples, evince the merit in handling high exon to sample size ratio datasets.
Isoform Network
A rich genome-wide resource of mouse networks at the isoform level, which was generated using a unique framework that was originally developed to infer isoform functions. This network was built through integrating heterogeneous genomic and protein data, including RNA-seq, exon array, protein docking and pseudo-amino acid composition. Through simulation and cross-validation studies, we demonstrated the accuracy of the algorithm in predicting isoform-level functional relationships. We showed that this network enables the users to reveal functional differences of the isoforms of the same gene, as illustrated by literature evidence with Anxa6 (annexin a6) as an example.
0 - 0 of 0 results
1 - 1 of 1 result

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.