IsomiRage statistics

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IsomiRage specifications


Unique identifier OMICS_06292
Name IsomiRage
Software type Framework/Library
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Java
Computer skills Advanced
Stability Stable
Maintained Yes


No version available

Publication for IsomiRage

IsomiRage citations


Chronic low dose exposure to a mixture of environmental endocrine disruptors induces microRNAs/isomiRs deregulation in mouse concomitant with intratesticular estradiol reduction

Sci Rep
PMCID: 5469815
PMID: 28611354
DOI: 10.1038/s41598-017-02752-7

[…] s 256). Afterwards, we undertook the identification and quantification of pre-miRNAs and mature miRNAs using HTSeq script and a general feature format file (GFF) that was downloaded from miRBase v21. IsomiRage software was used for isomiRs detection and quantification. […]


Serum microRNA signatures as 'liquid biopsies' for interrogating hepatotoxic mechanisms and liver pathogenesis in human

PLoS One
PMCID: 5435338
PMID: 28545106
DOI: 10.1371/journal.pone.0177928
call_split See protocol

[…] ed) separately against the HC. The results were filtered for significantly altered miRNAs applying a false discovery rate below 5 percent as described previously []. For isomiR quantification we used Isomirage [] to map all reads to an isomiR database derived from miRBase. The reads were converted to proportions and for each condition the predominant isomiR per miRNA was identified. Based on the r […]


miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets

PMCID: 4523495
PMID: 25659536
DOI: 10.1016/j.mce.2015.01.035

[…] ated modification is adenylation, catalyzed by the adenosine deaminase (ADAR) family of enzymes (). The expression isomiRNAs is dynamic, with differences between cell types and tissues. A tool called IsomiRage is available for profiling the miRNAs/isomiRs and corresponding differential expression patterns using Illumina next-generation sequencing datasets of s […]


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IsomiRage institution(s)
Center for Genomic Science of IITASEMM, Istituto Italiano di Tecnologia (IIT), Milan, Italy

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