iStable statistics
iStable specifications
Information
| Unique identifier | OMICS_07140 |
|---|---|
| Name | iStable |
| Interface | Web user interface |
| Restrictions to use | None |
| Programming languages | Java, PHP |
| Computer skills | Basic |
| Stability | Stable |
| Requirements |
LIBSVM
|
| Maintained | Yes |
Publication for iStable
IStable: off-the-shelf predictor integration for predicting protein stability changes.
iStable citations
(12)A case of Raine syndrome presenting with facial dysmorphy and review of literature
[…] sequence deviation (rmsd) of 0.3 ao was observed between native and mutant structure, indicating changes in the loop regions of the superimposed structure. a decrease instability was predicted by istable with a confidence score of 0.605. furthermore, i-mutant predicted a large decrease in protein stability due to the variant p.ser410thr with δδg value of − 1.37 kcal/mol (fig. ).fig. 3, […]
Accurate prediction of functional, structural, and stability changes in PITX2 mutations using in silico bioinformatics algorithms
[…] of pitx2, sequence in fasta format was obtained from ncbi database (np_001191327.1)., eight different protein stability programs (duet, sdm, mcsm i-mutant3.0, mupro, iptree-stab, cupsat, and istable) were used to predict the effects of missense mutations on the stability of pitx2 protein. duet is a web server that uses integrated computational approach to predict effect of missense […]
Functional analysis implicating the SNP rs61552325 in ERBB2 as an effector for androgen insensitive prostate cancer cell invasion
[…] polymorphism plays a central role in the mechanism of metastasis for androgen-insensitive pca., the stability and pathogenicity of erbb2 were predicted using four tools i-mutant suite [–], istable [], polyphen-2 [] and hoipe [], and revealed that the mutation pro1140ala was very damaging and decreased protein stability (table ). structural stability analysis performed by the i-mutant […]
Structure of the homodimeric androgen receptor ligand binding domain
[…] bioinformatics programs were used to assess the impact of point mutations on the stability of monomeric versus dimeric ar-lbd conformations: cupsat (ref. ), smd (ref. ), polyphen (ref. ) and istable (ref. ). all mutations were in addition visually inspected using pymol. folding race (ref. ) was used to predict the changes in folding rates upon mutation., pc-3, cos-7 and hep3b cells […]
Integrated metagenomic data analysis demonstrates that a loss of diversity in oral microbiota is associated with periodontitis
[…] variate logistic regression model with alpha-diversity as the independent variable and the probability of disease status as the response variable. the fitted values are in table , and the final model istable 1 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \u […]
Enhanced candicidal compound production by a new soil isolate Penicillium verruculosum MKH7 under submerged fermentation
[…] are given in table . regression analysis was performed to fit the response function (metabolite production) with the experimental data. the second-order polynomial equation for metabolite production istable 4 2\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \ […]
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