ITALICS specifications


Unique identifier OMICS_02064
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 2.40.0
Stability Stable
stats, R(>=2.0.0), GLAD, DBI, affxparser, oligo, oligoClasses, pd.mapping250k.sty, pd.mapping250k.nsp, ITALICSData, pd.mapping50k.xba240, pd.mapping50k.hind240
Maintained Yes


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Publication for ITALICS

ITALICS in publications

PMCID: 2891634
PMID: 20492709
DOI: 10.1186/1471-2407-10-222

[…] and hybridized according to manufacturer's recommendations., intensity signals data from genechip® human mapping 50 k xba array or genome-wide human snp array 6.0 were normalized and analyzed using italics (iterative and alternative normalization and copy number calling for affymetrix single nucleotide polymorphism [snp] arrays) algorithm [] or partek genomic suite (partek inc., st louis, mo, […]

PMCID: 2756404
PMID: 19285540
DOI: 10.1016/j.bbcan.2009.03.001

[…] the length of pcr fragments and gc content, and uses the average of at least 5 “best-fit” normal samples that show the least variation between arrays as a control . a recently published algorithm, italics, addresses the problems of pcr kinetics plus additional sources of nonrelevant variation between the probe quartet intensities, such as systematic variation and spatial effects, and uses […]

PMCID: 2656897
PMID: 19055754
DOI: 10.1186/bcr2204

[…] at a 1:500 dilution (lab vision, interchim, clichy, france)., dna and rna were purified as described []. for genomic arrays, affymetrix genechip human mapping 100 k was normalised and analysed using italics (iterative and alternative normalization and copy number calling for affymetrix snp arrays) algorithm []. the segmentation of the genomic profile was performed using glad (gain and loss […]

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ITALICS institution(s)
Institut Curie, Service de Bioinformatique, INSERM, U900, CNRS UMR144, Institut Curie, Translational Research Department, Paris, France

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