ITCell specifications

Information


Unique identifier OMICS_31856
Name ITCell
Interface Web user interface
Restrictions to use None
Input data An antigen sequence of interest, an MHCII allele sequence, and a TCR β or α+β variable region sequence.
Input format FASTA
Output data A list of potential epitopes as well as structural models of the pMHCII and pMHCII-TCR complexes.
Computer skills Basic
Stability Stable
Registration required Yes
Maintained Yes

Maintainers


  • person_outline Dina Schneidman-Duhovny
  • person_outline Andrej Sali

Additional information


http://modbase.compbio.ucsf.edu/itcell/help.cgi?type=help

Publication for ITCell

ITCell institution(s)
Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, San Francisco, CA, USA; Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, USA; California Institute for Quantitative Biosciences (QB3), University of California at San Francisco, San Francisco, CA, USA; Graduate Group in Biophysics, University of California at San Francisco, San Francisco, CA, USA; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel; Uniformed Services University of the Health Sciences, Bethesda, MD, USA; Bayer HealthCare, San Francisco, CA, USA
ITCell funding source(s)
Supported by grants from the National Institute of Health (F32CA168150, R21CA186077, R01 GM083960, and P41GM103481), NHLBI (1RC2HL101851 and R01 HL130448), and Bayer Healthcare Pharmaceuticals.

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