iTM-score specifications


Unique identifier OMICS_25466
Name iTM-score
Alternative name interfacial Template Modeling score
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


No version available


  • person_outline Jeffrey Skolnick

Publication for interfacial Template Modeling score

iTM-score citation


Protein Docking by the Interface Structure Similarity: How Much Structure Is Needed?

PLoS One
PMCID: 3278447
PMID: 22348074
DOI: 10.1371/journal.pone.0031349
call_split See protocol

[…] continuous fragments of polypeptide chains, to limit the summation to the template interface and the corresponding aligned target residues in the TM-score calculation. This makes it equivalent to the iTM-score, recently introduced by Gao and Skolnick . In general, TM-scores <0.2 indicate no fold similarity, whereas scores >0.5 point to similar folds , . Significant alignments were defined accordin […]

iTM-score institution(s)
Center for the Study of Systems Biology School of Biology, Georgia Institute of Technology, Atlanta, GA, USA
iTM-score funding source(s)
Supported by the National Institutes of Health Grant No. GM-48835.

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