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iview specifications


Unique identifier OMICS_03798
Name iview
Interface Web user interface
Restrictions to use None
License Apache License version 2.0
Computer skills Basic
Stability Stable
Maintained Yes

Publication for iview

iview citations


Econazole nitrate inhibits PI3K activity and promotes apoptosis in lung cancer cells

Sci Rep
PMCID: 5740072
PMID: 29269744
DOI: 10.1038/s41598-017-18178-0

[…] low idock score (in terms of binding free energy) and a high RF score (in terms of binding affinity). Then, the top-scoring compounds were visually examined using the convenient web-based visualizer iview in the context of PI3K╬▒ using the X-ray crystal structure of the highest resolution, i.e., PDB code 4JPS. Finally, commercially available compounds were purchased and subsequently validated in v […]


Identification of Clinically Approved Drugs Indacaterol and Canagliflozin for Repurposing to Treat Epidermal Growth Factor Tyrosine Kinase Inhibitor Resistant Lung Cancer

PMCID: 5712561
PMID: 29238696
DOI: 10.3389/fonc.2017.00288

[…] nked in ascending order of their estimated binding free energy. The docking results (predicted binding poses of the compounds) can be openly visualized by accessing http://istar.cse.cuhk.edu.hk/idock/iview/?3W2R-dbap+fda+npc(The PDB ID 3W2R can be changed to 4I22, 4RJ8, or 5HG7 to view the other docking results using the corresponding protein conformation). The top-scoring compounds were manually […]


Web3DMol: interactive protein structure visualization based on WebGL

Nucleic Acids Res
PMCID: 5570197
PMID: 28482028
DOI: 10.1093/nar/gkx383

[…] e.js (http://threejs.org/), while PV and 3DMol.js directly use low-level APIs. These tools offer basic solutions to present molecules in web browsers. GLmol is reused in several applications, such as iview (http://istar.cse.cuhk.edu.hk/iview/) () and ChemDoodle (http://web.chemdoodle.com/) (); PV is the default visualization engine of SWISS-MODEL (http://www.swissmodel.expasy.org/) (); and both NG […]


Web based volume slicer for 3D electron microscopy data from EMDB

J Struct Biol
PMCID: 4819904
PMID: 26876163
DOI: 10.1016/j.jsb.2016.02.012

[…] ed viewer that does this () but given the diminishing support for Java applets in modern browsers it is becoming increasingly likely that we will need to consider other solutions such as WebGL (e.g., iview (); http://istar.cse.cuhk.edu.hk/iview/). Integrated visualisation of cellular and molecular structure data will require overlaying segmentations onto map slices in the Volume browser. Unfortuna […]


Adapalene inhibits the activity of cyclin dependent kinase 2 in colorectal carcinoma

PMCID: 4626183
PMID: 26398439
DOI: 10.3892/mmr.2015.4310

[…] illustrates the conformation of CDK2 in complex with ADA in a three-dimensional manner predicted by iview (). shows the intermolecular interaction diagram in a two-dimensional manner using PoseView (). ADA was predicted to reside in the adenosine triphosphate-binding site of CDK2 and interact with […]


In Silico Identification and In Vitro and In Vivo Validation of Anti Psychotic Drug Fluspirilene as a Potential CDK2 Inhibitor and a Candidate Anti Cancer Drug

PLoS One
PMCID: 4493148
PMID: 26147897
DOI: 10.1371/journal.pone.0132072

[…] d and ranked according to their average predicted binding affinity across 44 X-ray crystal structures of CDK2. Their predicted free energy values are provided in . The docking prediction results with iview visualization [] are freely available at http://istar.cse.cuhk.edu.hk/idock/iview/?1GZ8-dbap and http://istar.cse.cuhk.edu.hk/idock/iview/?1GZ8-fda. plots the distribution of the average idock […]

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iview institution(s)
Department of Computer Science and Engineering, Chinese University of Hong Kong, Hong Kong, China; Graduate School of Medicine, Kyoto University, Kyoto, Japan
iview funding source(s)
Partly supported by Grant-in-Aid for JSPS Fellows (Grant Number 11J04341).

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