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Jenner-predict specifications

Information


Unique identifier OMICS_20485
Name Jenner-predict
Interface Web user interface
Restrictions to use None
Input data Proteine sequence, Proteome of listed bacteria
Input format FASTA
Output data URL link
Computer skills Basic
Stability Stable
Maintained Yes

Maintainers


  • person_outline EpiCombFlu
  • person_outline Chittaranjan Rout
  • person_outline Ankit Gupta

Additional information


http://14.139.240.55/vaccine/tutorial.html

Publication for Jenner-predict

Jenner-predict citations

 (6)
library_books

Proteomic and bioinformatic pipeline to screen the ligands of S. pneumoniae interacting with human brain microvascular endothelial cells

2018
Sci Rep
PMCID: 5869694
PMID: 29588455
DOI: 10.1038/s41598-018-23485-1

[…] athogen-independent predictor of the whole protein sequence) was used for prediction of antigenicity. Proteins larger than 1000 size were analyzed in chains. Protein immunogenicity was evaluated with Jenner Predict algorithm (http://14.139.240.55/vaccine/validation.html) for prediction of protein vaccine candidates. […]

library_books

Vaccines Meet Big Data: State of the Art and Future Prospects. From the Classical 3Is (“Isolate–Inactivate–Inject”) Vaccinology 1.0 to Vaccinology 3.0, Vaccinomics, and Beyond: A Historical Overview

2018
PMCID: 5845111
PMID: 29556492
DOI: 10.3389/fpubh.2018.00062

[…] assist researchers in vaccine discovery and design (, ). Databases of vaccine candidates, such as MalVac (), or Vaxar (), software tools such as Vaxjo (), VIOLIN (–), NERVE (), Vaxign (), Vacceed (), Jenner-predict server (), EpiToolKit (), iVax (), or VaxiJen (), have been specifically implemented for vaccinology to enable prediction of vaccine antigens or adjuvants.A successful example of ration […]

library_books

Identification of New Features from Known Bacterial Protective Vaccine Antigens Enhances Rational Vaccine Design

2017
Front Immunol
PMCID: 5662880
PMID: 29123525
DOI: 10.3389/fimmu.2017.01382

[…] has not been widely appreciated. Other criteria including signal peptides, conserved domains, and biological function analysis () have been used in different RV tools [e.g., NERVE (), Vaxign (), and Jenner-predict server ()], and machine-learning techniques are also applied to vaccine design studies (, ). However, the significance and association of above criteria with the protectiveness of bacte […]

library_books

Enhancing the Biological Relevance of Machine Learning Classifiers for Reverse Vaccinology

2017
Int J Mol Sci
PMCID: 5343848
PMID: 28157153
DOI: 10.3390/ijms18020312

[…] of filters until a subset of proteins are identified that represent potential vaccine candidates. Several utilities have been developed to implement filtering approaches to RV, for example Violin [], Jenner Predict [], and Ivax []. Drawbacks of filtering methods include the necessity of assessing large numbers of candidates in the laboratory and potential candidates with predicted subcellular loca […]

library_books

Structural and Computational Biology in the Design of Immunogenic Vaccine Antigens

2015
J Immunol Res
PMCID: 4615220
PMID: 26526043
DOI: 10.1155/2015/156241

[…] ely to have host cell adhesion functions. Raising antibodies against adhesins can have an inhibitory effect on colonization and infection []. Vaxign further added MHC I and MHC II epitope prediction. Jenner-Predict, while using some of the same filtering criteria as NERVE and Vaxign, put more weight on the known host-pathogen interaction domains on proteins []. Vacceed framework extended the vacci […]

library_books

iVAX: An integrated toolkit for the selection and optimization of antigens and the design of epitope driven vaccines

2015
PMCID: 4635942
PMID: 26155959
DOI: 10.1080/21645515.2015.1061159

[…] shed studies citing “immunoinformatics” or “computational vaccinology” (). Individual computational vaccinology tools, primarily for epitope prediction, are available from a range of sources, such as Jenner-predict and VaxiJen and IEDB. Figure 1. While a selection of computational vaccinology tools are available, most of these tools are ‘stand-alone’ algorithms that have not been integrated into a […]

Citations

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Jenner-predict institution(s)
Department of Biotechnology and Bioinformatics, Jaypee University of Information Technology, Waknaghat, Solan, Himachal Pradesh, India
Jenner-predict funding source(s)
Supported by Defense Research and Development Establishment (DRDE).

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