Permits to identify miRNA modules from their predicted miRNA targets as well as their expression data sets. The algorithm of Joung et al. is a population-based probabilistic search method. This model facilitates the incorporation of multiple heterogeneous information sources by adopting a balanced fitness function and co-evolutionary learning strategies. It also found miRNA–mRNA modules with significantly high fitness scores.
Center for Bioinformation Technology, Seoul National University, Seoul, Korea; School of Computing, Soongsil University, Seoul Korea; School of Computer Science and Engineering, Seoul National University, Seoul, Korea
JoungEtAl2007 funding source(s)
Supported in part by the National Research Laboratory Program of the Korea Ministry of Science and Technology (MOST) and in part by the Soongsil University Research Fund.