K-Map statistics

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Citations per year

Number of citations per year for the bioinformatics software tool K-Map

Tool usage distribution map

This map represents all the scientific publications referring to K-Map per scientific context
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Associated diseases


Popular tool citations

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K-Map specifications


Unique identifier OMICS_04918
Name K-Map
Interface Web user interface
Restrictions to use None
Programming languages Python
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Aik Choon Tan

Publication for K-Map

K-Map citations


An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer

BMC Genomics
PMCID: 4682411
PMID: 26681397
DOI: 10.1186/1471-2164-16-S12-S2

[…] For each TNBC cell lines, we used the top five ranking kinases (lowest chi-square p-values) as the query to K-Map for predicting effective compounds. Compounds with p < 0.05 are selected and sorted by connectivity scores. Table lists the top five compounds predicted by K-map based on the top five kinases f […]


Study of phosphorylation events for cancer diagnoses and treatment

PMCID: 4460185
PMID: 26055493
DOI: 10.1186/s40169-015-0059-0

[…] es, clinicians and scientists are interested in knowledge about which kinase-inhibitors can be applied for cancer treatments. Currently, a high-throughput kinase-inhibitor database is accessible, via K-MAP (http://tanlab.ucdenver.edu/kMap/kMapv1.0) [] and can be used to complement and design future clinical assays to study resistances and toxicities.There are a number of bioinformatics tools avail […]


Systems biology approaches for advancing the discovery of effective drug combinations

J Cheminform
PMCID: 4348553
PMID: 25741385
DOI: 10.1186/s13321-015-0055-9

[…] gulation of MCL1. Therefore, CMap is a useful tool for using gene signatures to predict drug combinations that may overcome drug resistance.Inspired by the CMap concept, Kim et al. recently developed K-Map (Kinase Inhibitor Connectivity Map) that systematically connects a set of query kinases to kinase inhibitors based on quantitative profiles of the kinase inhibitor activities []. Instead of gene […]


Computational methods for analysis and inference of kinase/inhibitor relationships

Front Genet
PMCID: 4075008
PMID: 25071826
DOI: 10.3389/fgene.2014.00196

[…] inity or by the strength of the inhibitory effect. This kind of network can aid in the identification and rationalization of drugs secondary effects and facilitate drug repositioning.KIDFamMap () and K-Map () are free web-databases in which kinase/inhibitor relationships, retrieved from different sources, are connected and integrated with other annotations to facilitate the at-a-glance investigati […]

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K-Map institution(s)
Translational Bioinformatics and Cancer Systems Biology Laboratory, Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA

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