KEGG ENZYME statistics

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KEGG ENZYME specifications


Unique identifier OMICS_21136
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes


  • person_outline Kae Morishima

KEGG ENZYME citations


Comparative genomics of the nonlegume Parasponia reveals insights into evolution of nitrogen fixing rhizobium symbioses

Proc Natl Acad Sci U S A
PMCID: 5960304
PMID: 29717040
DOI: 10.1073/pnas.1721395115
call_split See protocol

[…] predicted genes, we combined BLAST results against UniProt, TrEMBL, and nr with InterProScan results (custom script). To annotate Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) enzyme codes we used Blast2GO based on the nr BLAST results and InterProScan results. Finally, we filtered all gene models with hits to InterPro domains that are specific to repetitive elements. […]


The transcriptional landscape of Rhizoctonia solani AG1 IA during infection of soybean as defined by RNA seq

PLoS One
PMCID: 5587340
PMID: 28877263
DOI: 10.1371/journal.pone.0184095

[…] ellular component) was performed using a Fisher’s exact test and a FDR threshold <0.05. To determine to which metabolic pathways DEGs belonged, genes were assigned Kyoto Expedia of Genes and Genomes (KEGG) enzyme codes [] using the Blast2GO GO-enzyme code mapping function [] ( and Tables). […]


Chondroitin sulfate disaccharides modified the structure and function of the murine gut microbiome under healthy and stressed conditions

Sci Rep
PMCID: 5533764
PMID: 28754911
DOI: 10.1038/s41598-017-05860-6

[…] bial community impacted by CS disaccharides. Under the stressed condition, CS disaccharides significantly increased the abundance of 49 KEGG (Kyoto Encyclopedia of Genes and Genomes) enzymes while 15 KEGG enzyme classes were repressed by the treatment. For example, CS disaccharide supplementation led to a 2-fold increase in the abundance of polysaccharide export outer membrane protein (K01991, log […]


Internet Databases of the Properties, Enzymatic Reactions, and Metabolism of Small Molecules—Search Options and Applications in Food Science

Int J Mol Sci
PMCID: 5187839
PMID: 27929431
DOI: 10.3390/ijms17122039

[…] ses of enzymes are presented in . A search may be initiated in any database with the use of a dedicated search engine. ExplorEnz acts as a metabase by providing direct links to enzyme data in BRENDA, KEGG, ENZYME, and other databases not indicated in . Specialized databases dedicated to a specific category of enzymes, such as proteolytic enzymes (MEROPS) or enzymes catalyzing carbohydrate reaction […]


Metagenomic Profiling Reveals Lignocellulose Degrading System in a Microbial Community Associated with a Wood Feeding Beetle

PLoS One
PMCID: 3762729
PMID: 24023907
DOI: 10.1371/journal.pone.0073827

[…] eads were also functionally categorized via an RPS-BLAST comparison [] to the Clusters of Orthologous Gene (COG) database []. Reads were also assigned to Gene Ontology (GO) terms [] and classified to KEGG enzyme classes [] using BLAST2GO []; furthermore, reconstruction of metabolic pathways was conducted using MinPath (Minimal set of Pathways) parsimony analysis [] of KEGG Orthology (KO) assignmen […]


Discovery 2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria

Malar J
PMCID: 3637051
PMID: 23537208
DOI: 10.1186/1475-2875-12-116

[…] the ENZYME database hosted by ExPASy []. For Plasmodium species, the EC numbers were obtained from PlasmoDB. The EC numbers were subsequently used to link proteins to the enzyme data in BRENDA [] and KEGG ENZYME. Protein sequences from the DrugEBIlity database [], which contains druggability predictions on protein structures from PDB, were kindly provided by the ChEMBL group. A sequence similarity […]


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