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Kinase-substrate relationship inference software tools | Pathway analysis

Scansite
Web

Scansite

Searches for motifs within proteins that are likely to be phosphorylated by…

Searches for motifs within proteins that are likely to be phosphorylated by specific protein kinases or bind to domains such as SH2 domains, 14-3-3 domains or PDZ domains. In the graphical output,…

NetworKIN
Web

NetworKIN

A method for predicting in vivo kinase-substrate relationships, that augments…

A method for predicting in vivo kinase-substrate relationships, that augments intrinsic specificities of kinases with cellular context for kinases and phosphoproteins. Based on the latest human…

PTMapper
Desktop

PTMapper Post Translational Modification mapper

A bioinformatical platform to characterize the structures of phosphorylation…

A bioinformatical platform to characterize the structures of phosphorylation site-oriented PPI networks. From the quantitative phosphoproteome data on EGF-stimulated glioblastoma stem cells, our…

SELPHI
Web

SELPHI Systematic Extraction of Linked Phospho-Interactions

A computational workflow that aims to help non-bioinformaticians perform…

A computational workflow that aims to help non-bioinformaticians perform biological meaningful analyses of global phospho-proteomics datasets easily and to guide the design of downstream experiments…

PhosD
Algorithm

PhosD

Predicts kinase-substrate relationships based on protein domains with the…

Predicts kinase-substrate relationships based on protein domains with the assumption that kinase-substrate interactions are accomplished with kinase-domain interactions. PhosD identifies the kinases…

DynaPho
Web

DynaPho

Integrates various functional analysis methods to assist researchers in…

Integrates various functional analysis methods to assist researchers in analyzing and interpreting their large-scale time-series phosphoproteomics data. DynaPho is an integrative web tool for…

CEASAR
Algorithm

CEASAR

A strategy based on functional protein microarrays and bioinformatics to…

A strategy based on functional protein microarrays and bioinformatics to experimentally identify substrates for 289 unique kinases, resulting in 3656 high-quality kinase-substrate relationships…

iGPS
Desktop

iGPS in vivo GPS

A software package for the prediction of in vivo site-specific kinase-substrate…

A software package for the prediction of in vivo site-specific kinase-substrate relations mainly from the phosphoproteomic data. This work contributes to the understanding of phosphorylation…

PhosphoSiteAnal…
Desktop

PhosphoSiteAnalyzer

Retrieves kinase-substrate predictions from NetworKIN algorithm and contains…

Retrieves kinase-substrate predictions from NetworKIN algorithm and contains various statistical modules for further analysis. PhosphoSiteAnalyzer is a bioinformatical tool for analyzing…

PKIS
Web

PKIS

A protein kinase identification web server is presented for the identification…

A protein kinase identification web server is presented for the identification of the protein kinases responsible for experimentally verified P-sites at high specificity, which incorporates the…

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