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kinship specifications


Unique identifier OMICS_11091
Name kinship
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.6.4
Stability Stable
methods, stats, graphics, Matrix, quadprog, R(≥3.1.0)
Maintained Yes


No version available



  • person_outline Jason Sinnwell

Publications for kinship

kinship citations


CCDC102B confers risk of low vision and blindness in high myopia

Nat Commun
PMCID: 5934384
PMID: 29725004
DOI: 10.1038/s41467-018-03649-3
call_split See protocol

[…] eviation from Hardy–Weinberg equilibrium (P < 1.0 × 10−6), and samples with a call rate of <95% were excluded from the analysis. After this QC, 333 participants with estimated first- or second-degree kinship within Nagaham cohort samples (pi-hat > 0.35, PLINK ver. 1.07 []) were also excluded.Genotype imputation was performed using MACH software (http://www.sph.umic […]


Evidence for association between familial bipolar risk and ventral striatal volume

PMCID: 5884316
PMID: 29477586
DOI: 10.1016/j.jad.2018.02.015

[…] uded from the current analyses if they lacked good-quality structural magnetic resonance imaging data, or had missing relevant interview/questionnaire data. Further information about the HCP pedigree/kinship structure can be found at Individuals were excluded who had at least one parent wit […]


Family Based Genome Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus

PMCID: 5961220
DOI: 10.1167/iovs.17-23536

[…] The kinship coefficients for pairwise relationships across pedigrees were estimated from the SNP data using the KING software (provided in the public domain,∼wc9c/KING/ […]


Association of Raynaud’s phenomenon with a polymorphism in the NOS1 gene

PLoS One
PMCID: 5919461
PMID: 29698501
DOI: 10.1371/journal.pone.0196279
call_split See protocol

[…] istical analysis was performed using R statistical software with the package GenABEL []. We used linear regression model to analyse association between RP and the SNPs accounting for age, sex and the kinship shared by twins in a pair. The p-values were obtained through experiment-wise permutation testing (n = 200) and the significance threshold was set at p = 0.05. […]


A genome wide association study of red blood cell fatty acids and ratios incorporating dietary covariates: Framingham Heart Study Offspring Cohort

PLoS One
PMCID: 5898718
PMID: 29652918
DOI: 10.1371/journal.pone.0194882

[…] ovariates (see , which assigns each dietary fatty acid to the same red blood cell fatty acid and the other fatty acids derived from it utilizing information from well-known fatty acid pathways) and a kinship matrix summarizing the family structure of the Framingham data using the lmekin function in R []. This function implements a linear mixed effects model to predict the fatty acid using the kins […]


Chemical composition of axillary odorants reflects social and individual attributes in rhesus macaques

PMCID: 5871651
PMID: 29606788
DOI: 10.1007/s00265-018-2479-5

[…] r, the bacterial communities contributing to social odors in meerkats varied between groups independent of relatedness (Leclaire et al. ). In rhesus macaques, group membership is less confounded with kinship than in owl monkeys because groups also contain a large number of unrelated individuals (Pfefferle et al. ) and our analysis indeed detected some group-specificity in rhesus chemical profiles. […]


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kinship institution(s)
Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Chinahester, MN, USA

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