An online tool to explore established and potential gene-disease associations in the context of other biomedical relations. Knowledge.bio provides access to a network of interconnected concepts mined from more than 20,000,000 PubMed abstracts. We integrate explicit connections identified by the SemRep system from the US National Library of Medicine with the Implicitome from the Leiden University Medical Center. The Implicitome provides predicted relationships between genes and diseases based on 'concept profile' technology.
STAR Informatics/Delphinai Corporation, Port Moody, BC, Canada; Department of Molecular and Experimental Medicine, The Scripps Research Institute, Road, La Jolla, CA, USA; Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands
Knowledge.bio funding source(s)
This work was supported by the US National Institute of Health (grants GM089820 and U54GM114833 to AIS) and by the Scripps Translational Science Institute with an NIHNCATS Clinical and Translational Science Award (CTSA; 5 UL1 TR001114). Funding from the European Commission (FP-7 project RD-Connect, grant agreement No. 305444), and ODEX4all (NWO 650.002.002) are gratefully acknowledged.