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KO specifications


Unique identifier OMICS_05360
Name KO
Alternative name KEGG Orthology
Restrictions to use None
Maintained Yes

Publication for KEGG Orthology

KO citations


Transcriptomic analysis of crustacean molting gland (Y organ) regulation via the mTOR signaling pathway

Sci Rep
PMCID: 5943448
PMID: 29743490
DOI: 10.1038/s41598-018-25368-x

[…] built-in KEGG pathways (http://www.genome.jp/kegg/pathway.html). KO_insect-specific.fasta was blasted against the KEGG annotations to the Kyoto Encyclopedia for Genes and Genomes (KEGG) pathways and KEGG orthology (KO) (http://www.genome.jp/kegg/ko.html) databases. The KEGG Automatic Annotation Server (KAAS) software (http://www.genome.jp/tools/kaas/) was used to obtain KO numbers to create a sum […]


Multilevel social structure and diet shape the gut microbiota of the gelada monkey, the only grazing primate

PMCID: 5935910
PMID: 29729671
DOI: 10.1186/s40168-018-0468-6

[…] of hydrocarbons known as terpenes, the largest class of plant secondary metabolites []. We also looked for specific enrichment of the three main cellulolytic enzyme categories: β-1,4-endoglucanases (KEGG orthology K01179), β-1,4-exoglucanases (K01225), and β-glucosidases (K05350) []. β-1,4-endoglucanases were significantly enriched in sheep relative to primates (p < 0.001 for all comparisons, unp […]


Comparative Metatranscriptomics of Wheat Rhizosphere Microbiomes in Disease Suppressive and Non suppressive Soils for Rhizoctonia solani AG8

Front Microbiol
PMCID: 5945926
PMID: 29780371
DOI: 10.3389/fmicb.2018.00859

[…] on average to the dominant pathways of Metabolism (32%), Unclassified KEGGs (31%), Genetic Information (22%), Environmental information Processing (6%), or other categories (9%). The number of unique KEGG orthology (KO) identifiers found for all 12 samples was 10,669.Differential expression analysis of KEGG functions revealed eight significant KEGG identifiers (P-value and FDR < 0.05, FC ≥ 2; Tabl […]


How Does Salinity Shape Bacterial and Fungal Microbiomes of Alnus glutinosa Roots?

Front Microbiol
PMCID: 5915629
PMID: 29720967
DOI: 10.3389/fmicb.2018.00651

[…] with PICRUSt using BIOM tools. Then, the BIOM file was normalized with normalize_by_copy_number.py and metagenomes were predicted as well as NSTI scores calculated with predict_metagenomes.py, using KEGG Orthology as the base for predictions. Finally, an.spf file was prepared with biom_to_stamp.py. Predicted metagenomes were analyzed at the KEGG Orthologs (KO) level with STAMP v.2.1.3 (), using t […]


mus 52 disruption and metabolic regulation in Neurospora crassa: Transcriptional responses to extracellular phosphate availability

PLoS One
PMCID: 5905970
PMID: 29668735
DOI: 10.1371/journal.pone.0195871
call_split See protocol

[…] . GO term enrichment was performed using the BayGO algorithm []. To identify metabolic pathways in which genes could be modulated in response to phosphate availability, annotation was performed using Kegg Orthology [], using the Kegg Automatic Annotation Server (KAAS) and N. crassa as a reference organism. Expression graphics were constructed using GraphPad Prism v 5.1 Software (LaJolla, CA, USA). […]


The influence of diet and environment on the gut microbial community of field crickets

Ecol Evol
PMCID: 5938447
PMID: 29760910
DOI: 10.1002/ece3.3977
call_split See protocol

[…] predict gene families of the bacterial communities in cricket guts, according to the online protocol (http://picrust.github.io/picrust/index.html), by referencing the sequenced 16S rRNA gene data to KEGG Orthology Database (Kanehisa & Goto, ). PICRUSt output was analyzed and visualized with STAMP version 2.1.3 (Parks, Tyson, Hugenholtz, & Beiko, ). Statistical significance was calculated using AN […]


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