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LaCyTools specifications


Unique identifier OMICS_15184
Name LaCyTools
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
License Apache License version 2.0
Computer skills Advanced
Version 1.0.1
Stability Stable
Python, Numpy, Scipy, Matplotlib, tkinter, pytables
Maintained Yes



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  • person_outline Manfred Wuhrer <>

Publication for LaCyTools

LaCyTools in publications

PMCID: 5797742
PMID: 29445378
DOI: 10.3389/fimmu.2018.00129

[…] system (dionex/thermo scientific, breda, the netherlands) coupled to a maxis impact qtof-ms (bruker daltonics, bremen, germany) as described previously ()., data processing was performed using lacytools (). separate analyte curation was performed for igg1 and igg3 for both serum and eluates. tryptic igg1 glycopeptides contained the peptide sequence eeqynstyr, while the peptide sequence […]

PMCID: 5473812
PMID: 28623326
DOI: 10.1038/s41598-017-03838-y

[…] no internal standard was needed as the sample was rich enough to ensure proper alignment without an internal standard. the alignment program is an in-house and open source program, based on the lacytools alignment tool. the alignment program is supplied with this manuscript and can be found in  of the supplementary information. briefly, an alignment procedure referred to as “targeted […]

PMCID: 5449507
PMID: 28620376
DOI: 10.3389/fimmu.2017.00608

[…] and 2-ab-labeled glucose oligomers from which the retention times for the individual glycans were converted to glucose units., for automated relative quantification of the glycopeptides by lacytools (version 1.0.1, build 8) (), the nanolc-ms files were converted to mzxml files. chromatograms were aligned based on at least six glycopeptide signals with a signal-to-noise ratio (s/n) […]

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LaCyTools institution(s)
Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands; Department of Biochemistry and Molecular Biology, Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia
LaCyTools funding source(s)
This work was supported by the Horizon Programme Zenith project funded by the Netherlands Genomic Initiative (project number: 93511033), the European Union (Seventh Framework Programs HighGlycan, grant number 278535 and IBD-BIOM, grant number 305479) and INTEGRA-LIFE (grant number 315997).

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