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LBtope specifications


Unique identifier OMICS_06715
Name LBtope
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


No version available


Unique identifier OMICS_06715
Name LBtope
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for LBtope

LBtope citations


Fundamentals and Methods for T and B Cell Epitope Prediction

J Immunol Res
PMCID: 5763123
PMID: 29445754
DOI: 10.1155/2017/2680160

[…] d using various string kernels that eliminate the need for representing the sequence into length-fixed feature vectors, SMVtrip was trained on length-fixed tripeptide composition vectors. ABCpred and LBtope methods consist on artificial neural networks (ANNs) trained on similar positive data, B-cell epitopes, but differ on negative data, non-B-cell epitopes. Negative data used for training ABCpred […]


A novel B and helper T cell epitopes based prophylactic vaccine against Echinococcus granulosus

PMCID: 5915707
PMID: 29713601
DOI: 10.15171/bi.2018.06

[…] (GenBank: AMX81438) has been served with the prediction of BE and TE. In order to improve the accuracy of computational epitope mapping, we used different online predictor servers, including ElliPro LBTope, BepiPred v1.0, BcePred, ABCpred, and Immune Epitope Database (IEDB) server (window size 7, threshold 1.0).- The BepiPred can predict potential epitopes based on a combination of a hidden Marko […]


In Silico Validation of D7 Salivary Protein derived B and T cell Epitopes of Aedes aegypti as Potential Vaccine to Prevent Transmission of Flaviviruses and Togaviruses to Humans

PMCID: 5712781
PMID: 29225429
DOI: 10.6026/97320630013366

[…] tion is enhanced by looking at its ability to transport efficiently without getting cleaved by the human proteasomes. In the prediction of class-I MHC binding Bcell epitopes, three programs, ABCPred, LBtope and BepiPred server were used in order to screen peptides predicted at least more than one program. In the prediction of protein 3D structure, four different programs were used to choose a best […]


DRREP: deep ridge regressed epitope predictor

BMC Genomics
PMCID: 5629616
PMID: 28984193
DOI: 10.1186/s12864-017-4024-8

[…] s when using a 75% specificity threshold, line (BCPred) designates BCPred’s predicted epitopes, line (ABCPred) designates ABCPred’s predicted epitopes, and similarly for EPitopia, CBTOPE, and finally LBtope. The true epitope locations are coloured green, and for each predictor, the incorrect predictions are coloured in red, and the correct are coloured blue. Fig. 4 […]


A Platform for Designing Genome Based Personalized Immunotherapy or Vaccine against Cancer

PLoS One
PMCID: 5104390
PMID: 27832200
DOI: 10.1371/journal.pone.0166372

[…] There are numerous methods such as BCEPred [], CBtope [], LBtope [], Discotope [], COBEpro [] available for predicting B-cell epitopes. We employed a standalone version of LBtope software for the prediction of linear B-cell epitopes. In order to predict immu […]


Computational approach for predicting the conserved B cell epitopes of hemagglutinin H7 subtype influenza virus

PMCID: 5038878
PMID: 27703505
DOI: 10.3892/etm.2016.3636

[…] amino acids to predict an epitope. While we can distinguish the epitopes by the scores, Reimer () demonstrated that the predictions made by BepiPred were better than a random guess for 8/11 proteins. LBtope is a novel tool for the prediction of epitopes that was developed by Singh et al () who exploited the availability of several thousands of experimentally verified epitopes and non-epitopes. Sin […]


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LBtope institution(s)
Bioinformatics Center, Institute of Microbial Technology, Chandigarh, India

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