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Citations per year

Number of citations per year for the bioinformatics software tool LCQUAN

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LCQUAN specifications


Unique identifier OMICS_33496
Software type Application/Script
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Windows
License Commercial
Computer skills Medium
Version 2.9
Stability Stable
Registration required Yes
Maintained Yes


No version available

LCQUAN citations


Plasma and breast milk pharmacokinetics of emtricitabine, tenofovir and lamivudine using dried blood and breast milk spots in nursing African mother–infant pairs

J Antimicrob Chemother
PMCID: 5890695
PMID: 29309634
DOI: 10.1093/jac/dkx507

[…] a TSQ Quantum Ultra triple quadrupole mass spectrometer (Thermo Electron Corporation, Hemel Hempstead, Hertfordshire, UK) equipped with a heated electrospray ionization source. Xcalibur Software and LCquan (version 2.6.1, Thermo Fisher Scientific, Hemel Hempstead, Hertfordshire, UK) were used for method set up, data acquisition, data processing and reporting.The assay was shown to yield consisten […]


Targeting mitochondrial oxidative phosphorylation eradicates therapy resistant chronic myeloid leukemic stem cells

Nat Med
PMCID: 5657469
PMID: 28920959
DOI: 10.1038/nm.4399

[…] ses were used and the mass accuracy obtained for all metabolites was below 5 ppm. Data were acquired with Thermo Xcalibur software.The peak areas of different metabolites were determined using Thermo LCquan software where metabolites were identified by the exact mass of the singly charged ion and by known retention time on the HPLC column. Commercially available standards compounds had been analys […]


Bortezomib resistance in multiple myeloma is associated with increased serine synthesis

PMCID: 5575874
PMID: 28855983
DOI: 10.1186/s40170-017-0169-9

[…]  ppm and further validated by concordance with retention times of standards. Peak areas of identified metabolites were in their respective linear range of detection. Metabolites were quantified using LCquan software (Thermo Scientific). Because cells were resuspended at equal cell densities, no substantial cell growth occurred between 0 and 8 h, and growth rates between resistant and sensitive cel […]


Quality by Design–Applied Liquid Chromatography Tandem Mass Spectrometry Determination of Enzalutamide Anti Prostate Cancer Therapy Drug in Spiked Plasma Samples

PMCID: 5576540
PMID: 28874884
DOI: 10.1177/1177390117726776

[…] : 35 V. High-performance liquid chromatography was performed using a Shimadzu SIL-20AC HT Autosampler with LC-20AD HPLC Pump; both were controlled by CBM-20A module. Software used to acquire data was LCQUAN 2.5.6, which is a 21 CFR Part 11-compliant solution for method development in LC-MS/MS. For the separation of ENZ from its matrix, a QbD-optimised isocratic mobile phase was used. This comprise […]


A first in human study of the novel HIV fusion inhibitor C34 PEG4 Chol

Sci Rep
PMCID: 5572697
PMID: 28842581
DOI: 10.1038/s41598-017-09230-0

[…] ed at m/z 313.1 → 246.1. Peak area ratios of compound to internal standard were utilized to construct a calibration curve with a weighting of 1/x2. Data acquisition and processing was performed using LCQuan software (Version 2.7, Thermo Scientific, Hemel Hempstead, UK). The assay calibration range was between 62.5–10,000 ng/mL; inter and intra-assay accuracy and precision at the assay limit of qua […]


Development, validation and clinical application of a method for the simultaneous quantification of lamivudine, emtricitabine and tenofovir in dried blood and dried breast milk spots using LC–MS/MS

PMCID: 5588985
PMID: 28651173
DOI: 10.1016/j.jchromb.2017.06.012

[…] uantum Ultra triple quadrupole mass spectrometer (Thermo Electron Corporation, Hemel Hempstead, Hertfordshire, UK) equipped with a heated electrospray ionisation source (H-ESI). Xcalibur Software and LCquan (version 2.6.1, Thermo Fisher Scientific, Hemel Hempstead, UK) were used for method setup, data acquisition, data processing and reporting.A solvent gradient programme (flow rate of 400 μL/min) […]

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LCQUAN institution(s)
Thermo Fisher Scientific, Waltham, MA, USA

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