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LPS-annotate
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A service for annotation of compositionally-biased regions, and searching for similar regions in other sequences. The algorithm defines compositional bias through a thorough search for lowest-probability subsequences (LPSs) (i.e., the least likely sequence regions in terms of composition). Users can (i) initially annotate compositionally biased (CB regions) in input protein or nucleotide sequences of interest, and then (ii) query a database of greater than 1,500,000 pre-calculated protein-CB regions, for investigation of further functional hypotheses and inferences, about the specific CB regions that were discovered, and their protein disorder propensities.
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