Performs comprehensive in silico analyses. LeTE-fusion gives an ideal estimation of peptide and variant peptide detections. It derives a realistic estimation of the percentage of detectable genome-annotated variants in shotgun mass spectrometry (MS) experiments using peptides with experimental evidence. This tool is useful for the assessment of feasibility of detecting other types of peptides or variations.
Institute of Information Science, Academia Sinica, Taipei, Taiwan; Institute of Chemistry, Academia Sinica, Taipei, Taiwan
LeTE-fusion funding source(s)
Supported by Academia Sinica, the Next-generation Pathway of Taiwan Cancer Precision Medicine Program (MP10604-000), the Taiwan Protein Project (MOST107-0210-01-19-02), and Ministry of Science and Technology of Taiwan (MOST106-2221-E-001-018).