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A web server for the automatic identification of pockets on protein surface using the Connolly surface and the degree of conservation. The use of the Connolly surface leads to slight improvements, the prediction re-ranking by conservation to significant improvements of the binding site predictions.

Specifications

Software type:
Package
Interface:
Command line interface
Restrictions to use:
None
Input format:
PDB
Operating system:
Unix/Linux
Computer skills:
Advanced
Stability:
Stable
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Interface:
Web user interface
Restrictions to use:
None
Input format:
PDB
Computer skills:
Basic
Stability:
Stable
View all reviews

0 user reviews

No review has been posted.

View all issues

0 issues

No open issue.

Documentation & support

Maintainer

  • Bingding Huang <bhuang at biotec.tu-dresden.de>

Credits

Institution(s)

Bioinformatics Group, Biotechnological Center, Technical University Dresden, Germany

Publications

  • (Huang and Schroeder, 2006) LIGSITEcsc: predicting ligand binding sites using the Connolly surface and degree of conservation. BMC structural biology.
    PMID: 16995956

Classification

Literature

  • (Laurie and Jackson, 2006) Methods for the prediction of protein-ligand binding sites for structure-based drug design and virtual ligand screening. Current protein & peptide science.
    PMID: 17073692

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