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limmaGUI | A graphical user interface for linear modeling of microarray data

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A graphical user interface (GUI) based on R-Tcl/Tk for the exploration and linear modeling of data from two-color spotted microarray experiments, especially the assessment of differential expression in complex experiments. limmaGUI provides an interface to the statistical methods of the limma package for R. It provides point and click access to a range of methods for background correction, graphical display, normalization, and analysis of microarray data. Arbitrarily complex microarray experiments involving multiple RNA sources can be accomodated using linear models and contrasts. Empirical Bayes shrinkage of the gene-wise residual variances is provided to ensure stable results even when the number of arrays is small. Integrated support is provided for quantitative spot quality weights, control spots, within-array replicate spots and multiple testing.

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limmaGUI forum

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limmaGUI classification

limmaGUI specifications

Unique identifier:
OMICS_02027
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU Lesser General Public License version 3.0
Stability:
Stable
Software type:
Package/Module
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Maintained:
Yes

limmaGUI distribution

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No versioning.

limmaGUI support

Documentation

Credits

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Publications

Institution(s)

Division of Genetics and Bioinformatics, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia

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