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LINC specifications


Unique identifier OMICS_33399
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License Artistic License version 2.0
Computer skills Advanced
Version 1.10
Stability Stable
Maintained Yes




No version available



  • person_outline Manuel Goepferich

LINC citations


Differentially Expressed lncRNAs in Gastric Cancer Patients: A Potential Biomarker for Gastric Cancer Prognosis

PMCID: 5595087
PMID: 28900495
DOI: 10.7150/jca.19980

[…] licated in various aspects of tumor, including carcinogenesis, progression, and metastasis -. Some lncRNAs are considered to be useful biomarkers to predict prognosis in GC patients, such as HULC and LINC00668 , . However, several limits are still concerned including small number of lncRNAs screened, inadequate samples, and lack of independent validation, the reliability and utility of prognostic […]


Role of the long non coding RNA PVT1 in the dysregulation of the ceRNA ceRNA network in human breast cancer

PLoS One
PMCID: 5302781
PMID: 28187158
DOI: 10.1371/journal.pone.0171661

[…] l genes, since they retain many of the miRNA binding sites.LncRNAs functioning as ceRNAs can be also observed in: mouse and human myoblasts, where the large intergenic non-coding RNA (lincRNA) called linc-MD1 controls muscle differentiation by targeting miR-133 and miR-135 to regulate the expression of MAML1 and MEF2C []; human embryonic stem cells, where linc-RoR competes with the transcription f […]


A 16 gene signature predicting prognosis of patients with oral tongue squamous cell carcinoma

PMCID: 5695251
PMID: 29158988
DOI: 10.7717/peerj.4062

[…] overall survival (). Overexpression of PARVB (parvin beta) increased cell migration capability and forecasted poor metastasis-free survival in OTSCC (). Overexpression of long non-coding RNA (lncRNA) LINC00673 promoted invasion and metastasis, and presented poor prognosis in OTSCC (). MicroRNA miR-26a and lncRNA MEG3 (maternally expressed 3) was reported to have an antitumor effect, and reduced mi […]


Activating transcription factor 3 is crucial for antitumor activity and to strengthen the antiviral properties of Onconase

PMCID: 5355296
PMID: 28035074
DOI: 10.18632/oncotarget.14302

[…] t of them were up-regulated in RNase-treated cells respective to untreated cells, whereas the other two were down-regulated. Common up-regulated genes are related to transcription regulation (HMBOX1, LINC00340, NEXN-AS1), immune response (CD86, IL6, IFIT2) and the last two are potential tumor suppressors (LRRC2 and SPINK6 [, ]). Common down-regulated genes participate in amino acid metabolism (PHG […]


Long Noncoding RNA Identification: Comparing Machine Learning Based Tools for Long Noncoding Transcripts Discrimination

Biomed Res Int
PMCID: 5153550
PMID: 28042575
DOI: 10.1155/2016/8496165

[…] oup of lncRNAs) classification, such as iSeeRNA (2012, web server and Linux binary package available at [] and LincRNA Classifier based on selected features (linc-SF, 2013) []. iSeeRNA built a SVM model with three feature groups: ORF; adjoining nucleotides frequencies (GC, CT, TAG, TGT, ACG, and TCG); and conservation score obtained from Phast []. The clas […]


Molecular signatures associated with cognitive deficits in schizophrenia: a study of biopsied olfactory neural epithelium

PMCID: 5315541
PMID: 27727244
DOI: 10.1038/tp.2016.154

[…] onal fluency domains were significantly lower in SZ patients compared with control, we focused on the genes that correlated with these four domains (SMAD5, PABPC4L, RBM28, RAB4A, ERO1LB, CCL11, CD69, LINC01004, COA3, CBFA2T2). Two genes, SMAD family member 5 (SMAD5) and poly(A) binding protein, cytoplasmic 4-like (PABPC4L), positively correlated with the composite score, which is the most represen […]


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