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- Homo sapiens
Publication for Linc2GO
Long non coding RNA Databases in Cardiovascular Research
[…] R-CLIP) experiments and computational prediction methods. More specialized databases exist for evolutionary conservation (PhyloNONCODE ) and functional annotation based on ceRNA interaction networks (Linc2GO ). Expression profiles of non-coding and coding genes are further available from RNA-Seq experiments (lncRNAMap ) and microarray platforms (NRED ). Co-LncRNA identifies co-expressed coding gen […]
Identification of lncRNA associated competing triplets reveals global patterns and prognostic markers for cancer
[…] ve been integrated to predict miRNA–lncRNA interactions; for instance, miRcode predicts human miRNA targets based on lncRNAs in the GENCODE project () using the targetscan prediction algorithm, while Linc2GO identified miRNA–lncRNA interactions using miRanda and predicted lncRNA function based on the ceRNA hypothesis (). However, traditional prediction methods often have a high false positive rate […]
Competing endogenous RNAs (ceRNAs): new entrants to the intricacies of gene regulation
[…] ed ceRNA and transcriptional network. Besides the mass-action model there are also several other model systems reported (Bosia et al., ; De Giorgio et al., ; Figliuzzi et al., ; Noorbakhsh et al., ). Linc2GO, a lincRNA (long intergenic non-coding RNA) function annotation database was recently generated to predict lincRNA functions based on ceRNA hypothesis (Liu et al., ).The critical aspects of ce […]
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