LINKMFEX statistics

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Citations per year

Number of citations per year for the bioinformatics software tool LINKMFEX

Tool usage distribution map

This map represents all the scientific publications referring to LINKMFEX per scientific context
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Associated diseases

This word cloud represents LINKMFEX usage per disease context

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LINKMFEX specifications


Unique identifier OMICS_27366
Alternative name LINKage analysis for outcrossed families with Male or Female EXchange of the mapping parent
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Input format ASCII
Output format ASCII
Operating system Windows
Programming languages Visual Basic
License Academic Free License version 3.0
Computer skills Medium
Version 3.1
Stability No
Registration required No
Maintained Yes


No version available


LINKMFEX citations


A SNP Based Linkage Map of the Arctic Charr (Salvelinus alpinus) Genome Provides Insights into the Diploidization Process After Whole Genome Duplication

PMCID: 5295600
PMID: 27986793
DOI: 10.1534/g3.116.038026

[…] The high quality SNPs selected for mapping, and the microsatellite marker anchors, were assessed for genetic linkage using LINKMFEX (). The SNPs were split into three categories: heterozygous male, heterozygous female, and double heterozygote (DH) SNPs where both parents were heterozygotes. The SNPs where only a single pa […]


Genomic Instability of the Sex Determining Locus in Atlantic Salmon (Salmo salar)

PMCID: 4632069
PMID: 26401030
DOI: 10.1534/g3.115.020115

[…] icrosatellite marker was genotyped in this family using an ABI 377 automated DNA sequencer. The genotype data were added to the data for family Br5 from , and linkage analysis was performed using the LINKMFEX package (). […]


Construction of a high density, high resolution genetic map and its integration with BAC based physical map in channel catfish

PMCID: 4379976
PMID: 25428894
DOI: 10.1093/dnares/dsu038

[…] segregation-type markers only (AB × AA or AB × BB for female map and AA × AB or BB × AB for male map). The markers of segregation type 1 : 2 : 1 (AB × AB) were used to build the sex-averaged map. The LINKMFEX software (version 2.4, was used to perform linkage analysis for sex-specific markers, and OneMap (R package, version 2.0) was used for linkage a […]


Comparative Genome Mapping Between Chinook Salmon (Oncorhynchus tshawytscha) and Rainbow Trout (O. mykiss) Based on Homologous Microsatellite Loci

PMCID: 3852389
PMID: 24170738
DOI: 10.1534/g3.113.008003

[…] Sex-specific maps were generated using LINKMFEX V2.3 () to accommodate significant differences in recombination rates between males and females, frequently observed in salmonids. Here, the pairwise recombination fraction between markers, θ […]


Quantitative Trait Loci (QTL) Associated with Resistance to a Monogenean Parasite (Benedenia seriolae) in Yellowtail (Seriola quinqueradiata) through Genome Wide Analysis

PLoS One
PMCID: 3672171
PMID: 23750223
DOI: 10.1371/journal.pone.0064987
call_split See protocol

[…] Genotype scoring was performed by using LINKMFEX ver. 2.3 application package . The application can separate the allele genotypes which originate from males or females, and check the accuracy of genotypes in their progeny from parental male […]


Meiotic maps of sockeye salmon derived from massively parallel DNA sequencing

BMC Genomics
PMCID: 3563581
PMID: 23031582
DOI: 10.1186/1471-2164-13-521

[…] 12 families and in both the RAD tag data and the 5’-nuclease assays in the sequences family. The individual male and female maps from each family were combined where possible using MERGE, part of the LINKMFeX package []. […]

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LINKMFEX institution(s)
Roy Danzmann Dept. of Integrative Biology, University of Guelph, Guelph ON, Canada
LINKMFEX funding source(s)
Research supported by the Natural Sciences and Engineering Research Council of Canada (NSERC)

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