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LINUCS specifications


Unique identifier OMICS_21259
Alternative name LInear Notation for Unique description of Carbohydrate Sequences
Interface Web user interface
Restrictions to use None
Input data A structure using the extended, non-graphic nomenclature to describe complex carbohydrates.
Output data A linear, unique notation.
Programming languages C
Computer skills Basic
Stability Stable
Maintained Yes


No version available


  • person_outline Claus von der Lieth

Publication for LInear Notation for Unique description of Carbohydrate Sequences

LINUCS citations


GLYDE II: The GLYcan data exchange format

PMCID: 5611833
PMID: 28955652
DOI: 10.1016/j.pisc.2016.05.013

[…] e formats have been developed, and more than one can be used in a single database or software application. These sequence formats include linearized representations of the branched sequences, such as LINUCS (), the BCSDB format () and LinearCode® (), as well as connection table representations, such as GlycoCT (), WURCS () and KCF () and XML representations, such as CabosML (). The development of […]


Glycoblocks: a schematic three dimensional representation for glycans and their interactions

Acta Crystallogr D Struct Biol
PMCID: 5297921
PMID: 28177314
DOI: 10.1107/S2059798316013553

[…] ctions on their three-dimensional conformations, it is precisely this nonlinear nature of glycans that poses a challenge in terms of two-dimensional representation. A number of sequence formats (e.g. LINUCS, Bohne-Lang et al., 2001; GLYCO-CT, Herget et al., 2008) have been developed for creating textual renditions of branched polysaccharides, each with their respective strengths and pitfalls. Many […]


A Computational Framework for the Automated Construction of Glycosylation Reaction Networks

PLoS One
PMCID: 4076241
PMID: 24978019
DOI: 10.1371/journal.pone.0100939

[…] esidues in the substrate structure that prevent enzyme activity, and targetBranch describes the substrate characteristics of the target branch where the enzyme acts. These structures are displayed in LINUCS (Linear Notation for Unique description of Carbohydrate Sequences) format in , or they can be graphically viewed by clicking the plot button of the Enzyme Viewer. This visualization component, […]


The DBCLS BioHackathon: standardization and interoperability for bioinformatics web services and workflows. The DBCLS BioHackathon Consortium*

J Biomed Semantics
PMCID: 2939597
PMID: 20727200
DOI: 10.1186/2041-1480-1-8

[…] the branched nature of glycans and the fact that the linkage between individual glycosyl residues can be complex. Several different successful representation protocols have been developed, including LINUCS (Linear Notation for Unique description of Carbohydrate Sequences) [], and KCF (KEGG Chemical Function) []. Recently, it became clear that interoperability of the various databases and web serv […]


GlycoForm and Glycologue: two software applications for the rapid construction and display of N glycans from mammalian sources

BMC Res Notes
PMCID: 2904795
PMID: 20565879
DOI: 10.1186/1756-0500-3-173

[…] ology are relatively few in number at present, applications for the construction and display of branched carbohydrate structures are beginning to appear. LiGraph, a web-based application based on the LINUCS linear notation [], is able to draw JPG and SVG images from a linear string representation of a sugar. LiGraph supports a wide variety of symbol formats, including the Heidelberg, Tokyo, Consor […]


Analysis and validation of carbohydrate three dimensional structures

PMCID: 2631634
PMID: 19171971
DOI: 10.1107/S0907444909001905

[…] he existence of exocyclic O atoms) and then builds a stereocode string to identify the monosaccharide residue type of these rings (Lütteke et al., 2004). The detected carbohydrate chains are given in LINUCS notation, a linear and unique description of carbohydrate chains (Bohne-Lang et al., 2001). The im­plementation of these data into the database (Lütteke et al., 2006), the form […]


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LINUCS institution(s)
German Cancer Research Centre, Central Spectroscopic Department, Heidelberg, Germany; University of Applied Sciences Darmstadt, Department for Information and Knowledge Management, Darmstadt, Germany

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