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Number of citations per year for the bioinformatics software tool LipidSearch
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chevron_left Statistical analysis Lipid quantification Lipid identification Peak detection Chromatogram alignment Retention time correction chevron_right
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Protocols

LipidSearch specifications

Information


Unique identifier OMICS_02513
Name LipidSearch
Software type Package/Module
Interface Command line interface
Restrictions to use License purchase required
Operating system Unix/Linux
License Commercial
Computer skills Advanced
Stability Stable
Maintained No

Versioning


No version available

Publication for LipidSearch

LipidSearch citations

 (23)
call_split

Lipidomics Analysis of Behavioral Variant Frontotemporal Dementia: A Scope for Biomarker Development

2018
PMCID: 5835505
PMID: 29541056
DOI: 10.3389/fneur.2018.00104
call_split See protocol

[…] negative polarities. The samples were run in a random order (generated using Microsoft Excel). This is important to avoid batch effects/changing instrument performance effects. Data were analyzed in LipidSearch software 4.1.16. Data were searched against the standard Lipidsearch database with all common mammalian lipid classes included. The search results were then grouped according to sample typ […]

library_books

Discovery of Phosphatidic Acid, Phosphatidylcholine, and Phosphatidylserine as Biomarkers for Early Diagnosis of Endometriosis

2018
Front Physiol
PMCID: 5787104
PMID: 29410629
DOI: 10.3389/fphys.2018.00014

[…] pectra from UHPLC-ESI-HRMS were exported as raw files by Xcalibur (Thermo Scientific, San Jose, CA). Three-dimensional data set including m/z-values, retention times, and peak areas were extracted by LipidSearch software (Thermo Scientific, San Jose, CA) to perform lipids identification and evaluate matching degrees by A, B, C, D four grades. Orthogonal projection to latent structures discriminant […]

library_books

Host triacylglycerols shape the lipidome of intracellular trypanosomes and modulate their growth

2017
PLoS Pathog
PMCID: 5760102
PMID: 29281741
DOI: 10.1371/journal.ppat.1006800

[…] select ion exclusion was set to 8 s, and the HCD (higher-energy collisional dissociation) fragmentation ramp was set to 15, 25, and 35 NCE (normalized collision energy). All data were analyzed using LipidSearch Software Version 4.2 (Thermo Scientific) and all identified species (A, B and C quality) were validated manually as detailed in Supporting Information: Supplemental Methods. […]

library_books

Lipidomics Reveals Cerebrospinal Fluid Signatures of ALS

2017
Sci Rep
PMCID: 5732162
PMID: 29247199
DOI: 10.1038/s41598-017-17389-9

[…] After the extraction of lipids, lipidomics profiles were performed by high-resolution mass spectrometry (HRMS). LipidSearch™ and TraceFinder™ version 3.3 software (Thermo Fisher Scientific) were used for the characterization of lipid species.Briefly, CSF samples were thawed, centrifuged at 3000 g for 5 minutes, […]

library_books

Serial omics of P53−/−, Brca1−/− Mouse Breast Tumor and Normal Mammary Gland

2017
Sci Rep
PMCID: 5674068
PMID: 29109428
DOI: 10.1038/s41598-017-15132-y

[…] red from m/z 225-1450 in MS1 mode and the resolution was set to 70,000 for MS1 and 35,000 for MS2. MS1 and MS2 target values were set to 5e5 and 1e6, respectively. Lipidomics data were analyzed using LipidSearch 4.1.9 software (Thermo Fisher Scientific) and Elements for Metabolomics (Proteome Software) NIST database incorporated. […]

library_books

Engineered FGF19 eliminates bile acid toxicity and lipotoxicity leading to resolution of steatohepatitis and fibrosis in mice

2017
PMCID: 5721409
PMID: 29404440
DOI: 10.1002/hep4.1108

[…] h‐performance LC system coupled to a Q Exactive hybrid quadrupole‐Orbitrap MS (Thermo Fisher Scientific). A Hypersil GOLD C18 analytic column (100 × 2.1 mm, 1.9 μm) was used for separation of lipids. LipidSearch software (Thermo Fisher) was used for lipid molecular species identification and quantification. The lipid classes selected for the search were triacylglycerol, diacylglycerol, ceramide, c […]


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LipidSearch institution(s)
Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho-ku, Nagoya City, Aichi, Japan

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