Literature Lab specifications


Unique identifier OMICS_29229
Name Literature Lab
Alternative name Literature Lab PLUS
Software type Application/Script
Interface Command line interface
Restrictions to use Academic or non-commercial use
Operating system Unix/Linux, Windows
Programming languages Java
Computer skills Advanced
Stability Stable
Sun's Java Runtime environment
Maintained Yes


No version available


  • person_outline Phillip Febbo
  • person_outline Stephen Taylor
  • person_outline Mike Mulligan
  • person_outline David Slonina
  • person_outline Kimberly Stegmeir

Additional information

Publication for Literature Lab

Literature Lab citations


Multiple Transcriptome Data Analysis Reveals Biologically Relevant Atopic Dermatitis Signature Genes and Pathways

PLoS One
PMCID: 4696650
PMID: 26717000
DOI: 10.1371/journal.pone.0144316

[…] wn promising results in the treatment of AD []. However, targeting PPARA (peroxisome proliferator-activated receptor alpha) versus PPARG for drug development needs be evaluated.Further analysis using Literature Lab™ from Acumenta Biotech showed that the keratinocyte differentiation pathway was significantly (P = 0.0006) enriched in 36 out of the 89 ADGES (), many of which are components of the ‘ep […]


The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas

PLoS One
PMCID: 2933229
PMID: 20838435
DOI: 10.1371/journal.pone.0012548

[…] al tumor regression in animal models . Tenascin-C (TNC) is induced by TGFβ signaling , , and promotes invasion of glioma cells through matrix metalloproteinase 12 .Both Ingenuity Pathway Analysis and Literature Lab Analysis identified the Notch pathway as being differentially regulated in low grade and high-grade proneural gliomas. Several components of the Notch pathway, including DLL3 and HEY2 a […]

Literature Lab institution(s)
Institute for Genome Science and Policy, Duke University, Durham, NC, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA; Acumenta Corporation, Boston, MA, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Department of Pathology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA
Literature Lab funding source(s)
Supported by (Grant #CA-29-05), NCI grants CA89031 and CA123175, Acumenta, Inc and the Department of Pathology at Dana Farber Cancer Institute.

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