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LitInspector specifications


Unique identifier OMICS_01187
Name LitInspector
Interface Web user interface
Restrictions to use License purchase required
Input data Some gene synonyms or Entrez Gene, gene IDs and free text.
Output data Sentences from PubMed abstracts where genes, transcription factors and keywords such as tissues and diseases are highlighted.
Computer skills Basic
Stability Stable
Free trial Yes
Registration required Yes
Maintained Yes


  • person_outline Matthias Frisch

Additional information A user account for the Genomatix Software Suite is required.

Publication for LitInspector

LitInspector citations


Identification of genetic elements in metabolism by high throughput mouse phenotyping

Nat Commun
PMCID: 5773596
PMID: 29348434
DOI: 10.1038/s41467-017-01995-2

[…] pathways” and “selection of go terms describing metabolic processes” method sections, respectively. literature information on the function of the resulting list of genes was inspected using pubmed, litinspector, and genecards. this iterative process produced a list of 51 genes with no information. the additional 20 genes represent those genes with known molecular information (based on go […]


GATA2/3 TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency

Proc Natl Acad Sci U S A
PMCID: 5692555
PMID: 29078328
DOI: 10.1073/pnas.1708341114

[…] tissue and cell type associations were analyzed using generanker tool by providing a corresponding list of gene names as input. this tool employs a proprietary literature data-mining algorithm (litinspector) based on all pubmed abstracts. individual tissues to gene associations found on sentence level are filtered for significance. names and synonyms are based on medical subject headings […]


Proteomic Analysis and Identification of Cellular Interactors of the Giant Ubiquitin Ligase HERC2

J Proteome Res
PMCID: 4324439
PMID: 25476789
DOI: 10.1021/pr501005v

[…] nci pathway interaction databases, and the memorial sloan-kettering cancer center’s cancer cell map. the basal pathway and network data were supplemented with information obtained from genomatix’ litinspector and matbase, uniprot, dbsubloc, stitch, gene expression atlas, reactome, and encode. nodes were color-coded according to nwd score with the median score 2.12., 293 t-rex cells grown […]


Hypoxia Mediated Downregulation of miRNA Biogenesis Promotes Tumor Progression

Nat Commun
PMCID: 4215647
PMID: 25351346
DOI: 10.1038/ncomms6202

[…] the promoter region of drosha was analyzed for potential transcription factor binding using matinspector (genomatix inc., germany), followed by analysis for a potential gene suppression role using litinspector (genomatix). the drosha promoter luciferase reporter assay was performed in a2780 and mcf7 cells using the dual luciferase system (switchgear genomics). cells were transfected using […]


Expression of RFC/SLC19A1 is Associated with Tumor Type in Bladder Cancer Patients

PLoS One
PMCID: 3132752
PMID: 21760912
DOI: 10.1371/journal.pone.0021820

[…] tfs that transactivate or repress transcription in response to requirements for folate cofactors control the net levels of rfc transcripts in tissues , . literature and pathway mining using the litinspector software showed that rfc (slc19a1) has potential interactions with creb1 (camp responsive element binding protein-1). cre/ ap-1-like consensus sequence is one of the two major sites […]


Exposure to Metal Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes

Environ Health Perspect
PMCID: 2898851
PMID: 20061215
DOI: 10.1289/ehp.0901300

[…] human database. a total of 150 kegg pathways were annotated for mir-222, 153 for mir-21, and 160 for mir-146a., to find signal transduction pathways related to mir-222, mir-21, and mir-146a, we used litinspector (, a literature search tool providing gene and signal transduction pathway mining within the national center for biotechnology information’s pubmed database […]

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LitInspector institution(s)
Genomatix Software, Munich, Germany

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