LncDisease specifications

Information


Unique identifier OMICS_11165
Name LncDisease
Software type Application/Script
Interface Graphical user interface
Restrictions to use None
Input data lncRNA sequence(s)
Input format FASTA
Operating system Unix/Linux
Computer skills Medium
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Versioning


No version available

Maintainer


  • person_outline Qinghua Cui

Publication for LncDisease

LncDisease citation

library_books

The Function and Therapeutic Potential of Long Non coding RNAs in Cardiovascular Development and Disease

2017
Mol Ther Nucleic Acids
PMCID: 5565632
PMID: 28918050
DOI: 10.1016/j.omtn.2017.07.014

[…] action in hypertension are not yet described, ANRIL affects cell adhesion, proliferation, and apoptosis, and MALAT1 modulates EC migration, sprouting, and proliferation. A novel bioinformatics tool, LncDisease, has been used to predict four human lncRNAs associated with hypertension, three of which were validated as dysregulated in Ang II-treated human VSMCs. Further investigation is required to […]

LncDisease institution(s)
Department of Biomedical Informatics, School of Basic Medical Sciences, Peking University, Beijing, China; MOE Key Lab of Cardiovascular Sciences, Peking University, Beijing, China; Mitchell Cancer Institute, University of South Alabama, Mobile, AL, USA; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, Beijing, China; Beijing Key Laboratory of Tumor Systems Biology, Peking University, Beijing, China
LncDisease funding source(s)
National Basic Research program of China [2012CB517506]; National High Technology Research and Development Program of China [2014AA021102]; National Natural Science Foundation of China [91339106, 81422006]; NIH/NCI R01 [1R01CA192395]; American Cancer Society Research Scholar [RSG-13–265–01-RMC]; NIH/NCI R21 [1R21CA160280, 1R21CA182754]

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