Collects experimentally validated IncRNA-chromatin interactions. LnChrom includes more than 382000 interaction pairs in up to 260 cell types/tissues in human and mouse. Users can access, for each interaction, to manually-curated metadata, including associated proteins/complexes, chromatin modifying factors and epigenetic modifications and diseases from original publications.
Informs about RNAs and DNA methylation. Lnc2Meth is an online resource that assists in comprehension of the expression of protein-coding or non-coding transcripts. Its purpose is to clarify the regulatory relationships between human lncRNAs and associated DNA methylation in different diseases.
A database that includes a comprehensive collection of transcriptome profiles of protein coding genes, miRNAs and lncRNAs perturbed by knockdown or overexpression in human and mouse. GPA offers a wealth of information on differential expression patterns, comprehensive functional and pathway characterizations, enrichments of transcriptional factors and miRNAs, information flow in interaction network, and associations with cancers and drugs, together with extensive manually curated phenotype annotations.
Consists of an integrative resource for microRNA and transcription factors analysis in cancer. ONCO.IO enables users to explore complex gene regulatory networks involved in cancer. This database contains data based on the manually curated annotation of experimentally verified molecular interactions described in the literature. It includes microRNAs, lncRNAs, mRNAs, signaling proteins and transcription factors interactions. Network analysis tools are also available.
Collects experimentally supported lncRNA–miRNA–mRNA interactions. LncCeRBase is an online resource developed to be helpful in understanding the regulatory mechanisms of lncRNA in complex diseases. Users select a lncRNA, miRNA or mRNA in the Browse page of the web site. It returns a list of matched lncRNA-miRNA-mRNA triplet associations, containing the name (lncRNA, miRNA, and mRNA), PubMed ID, associated disease/tissue, description, title and pathway name.
Provides all species and covers functional and disease-specific roles for all long non-coding RNAs (lncRNAs) validated. EVLncRNAs contains about 1543 lncRNAs from 77 species along with their annotated functions, interaction partners and relevant diseases. The database allows users to submit novel experimentally validated lncRNAs and related diseases or associated components. It can be searched by any keywords, such as lncRNA name, alias, disease name, experimental methods, associated components and level of interaction.
Enables to explore the transcriptional regulatory networks of noncoding RNAs (ncRNAs) and protein-coding genes (PCGs). ChIPBase is an open database that integrates many ChIPseq peak datasets of trans-acting factors, including transcription factors (TFs), transcription cofactors (TCFs), chromatin-remodeling factors (CRFs), other DNA-binding proteins and histone modifications. The database consists of nine web-based modules and tools.