LOCAS statistics

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Citations per year

Number of citations per year for the bioinformatics software tool LOCAS

Tool usage distribution map

This map represents all the scientific publications referring to LOCAS per scientific context
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LOCAS specifications


Unique identifier OMICS_00019
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


No version available



  • person_outline Juliane Klein

Publication for LOCAS

LOCAS citations


An optimized approach for local de novo assembly of overlapping paired end RAD reads from multiple individuals

R Soc Open Sci
PMCID: 5830760
PMID: 29515871
DOI: 10.1098/rsos.171589

[…] have assembled RPE reads into contigs using different assembly tools [,,], such as the de Bruijn Graph (DBG) based software Velvet [] and the Overlap-Layout-Consensus (OLC) based software CAP3 [] and LOCAS []. Davey et al. [] demonstrated that VelvetOptimiser was the best assembly tool for RAD data by comparing nine assembly tools. However, Hohenlohe et al. [] found CAP3 performed much better than […]


Special features of RAD Sequencing data: implications for genotyping

Mol Ecol
PMCID: 3712469
PMID: 23110438
DOI: 10.1111/mec.12084

[…] 2 sequences by locus or by allele and test assembly accordingly. As expected based on previous reports (Baxter et al. ; Willing et al. ), unoptimizing assemblers such as Velvet (Zerbino & Birney, ), LOCAS (Klein et al. ) and SOAPdenovo (Li et al. ) produce poor assemblies, because of considerable variation in coverage and heterozygosity across RAD loci. VelvetOptimiser produces the best assemblie […]

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LOCAS institution(s)
Chair of Algorithms in Bioinformatics, University of Tübingen, Tübingen, Germany; Genes and Disease Program, Center for Genomic Regulation and Universitat Pompeu Fabra, Barcelona, Spain; Department of Plant Developmental Biology, Max-Planck-Institute for Plant Breeding Research, Köln, Germany; Department of Molecular Biology, Max Planck Institute for Developmental Biology, Tübingen, Germany

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